Evidence map›Paper›PMID 36780095›Full record

SynthesisIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2023

Utility of high-flow nasal oxygen in comparison to conventional oxygen therapy during upper gastrointestinal endoscopic procedures under sedation: A systematic review and meta-analyses.

Puneet Khanna, Damarla Haritha, Aditi Das, Soumya Sarkar, Avishek Roy

Registry-linked trialOpen access · bronzeAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06756906 (Comparison of the Effects of High Flow Nasal Oxygen and Standard Nasal Oxygen Therapy in Preventing Hypoxia in Minor and Moderate Burn Patients Treated Under Sedation), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
9.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06756906 recruitingnot on this mapstarted 2024, after this paper: background citation

Comparison of the Effects of High Flow Nasal Oxygen and Standard Nasal Oxygen Therapy in Preventing Hypoxia in Minor and Moderate Burn Patients Treated Under Sedation

TypeobservationalSponsorAnkara City Hospital BilkentRan2024 to 2025Enrolled70ConditionsBurn Injury, Hypoxia, Sedation
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Optimizing Oxygenation during Gastrointestinal Endoscopy: The Rise of HFNC Therapy.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025
    Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Puneet KhannaDepartment of Anaesthesia, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi, 110 029, India.
Damarla HarithaDepartment of Anaesthesia, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi, 110 029, India.
Aditi DasDepartment of Paediatric Medicine, Kalawati Saran Children's Hospital, New Delhi, 110 001, India.
Soumya SarkarDepartment of Anesthesia and Critical Care, All India Institute of Medical Sciences, Bhubaneswar, 751 019, India. drsoumyasarkar@yahoo.co.in.ORCID http://orcid.org/0000-0003-0497-9909
Avishek RoyDepartment of Anaesthesia, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi, 110 029, India.
All India Institute of Medical Sciences · INAll India Institute of Medical Sciences Bhubaneswar · INKalawati Saran Children's Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSedation and analgesia are the integral components of modern-day upper gastrointestinal (GI) endoscopic procedures. Irrespective of the sedative agent, hypoxia is the most commonly encountered unwarranted event with sedation. The current study intends to scrutinize whether high-flow nasal oxygen (HFNO) is advantageous for providing respiratory support during upper GI endoscopic procedures over other conventional low-flow oxygen delivery modalities, e.g. nasal cannula, facemask, etc.

methodsAn extensive screening of electronic databases was done till July 31, 2022, after enlisting in International prospective register of systematic reviews (PROSPERO) (CRD42021245409). Randomized controlled trials (RCT), comparative cohort studies, case series, cross-sectional studies and case-control studies evaluating the utility of HFNO during upper GI endoscopy under sedation were included in this meta-analysis.

resultsWe retrieved eight randomized control studies and one longitudinal study with 3294 patients. The application of HFNO during endoscopy led to lesser incidence of desaturation spells (odds ratio [OR] = 0.23; 95% CI 0.11-0.48; I

conclusionHFNO is a novel option for upper GI endoscopy under sedation. CLINICAL TRIAL NUMBER AND REGISTRY URL: CRD42021245409 ( https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021245409 ).

Indexed as

Hypnotics and SedativesOxygenEndoscopy, GastrointestinalHumansHypoxiaOxygen Inhalation TherapyHypnotics and SedativesOxygenAdverse eventsEndoscopyHigh-flow nasal oxygenSedationUpper gastrointestinal system

Identifiers

PMID36780095
PMCPMC9924186
OpenAlexW4320480844

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.