Evidence map›Paper›PMID 36779191›Full record

ArticleFrontiers in cellular and infection microbiology2023

A zone-of-inhibition assay to screen for humoral antimicrobial activity in mosquito hemolymph.

Bianca Morejon, Kristin Michel

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Distinct roles of theCurrent research in insect science · 2026
    Article
  2. Article
  3. The expanded immunoregulatory protease network in mosquitoes is governed by gene coexpression.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Bianca MorejonDivision of Biology, Kansas State University, Manhattan, KS, United States.
Kristin MichelDivision of Biology, Kansas State University, Manhattan, KS, United States.
Kansas State University · US

Funding

The protease network that regulates innate immunity in mosquitoesR01AI140760 · NIAID · KANSAS STATE UNIVERSITY · PI MICHEL, KRISTIN · 2018 to 2022
$2.8M
NIAID NIH HHS R01 AI140760
6 · The paper itself

Abstract

In insects, antibacterial immunity largely depends on the activation of downstream signaling and effector responses, leading to the synthesis and secretion of soluble effector molecules, such as antimicrobial peptides (AMPs). AMPs are acute infection response peptides secreted into the hemolymph upon bacterial stimulation. The transcription of innate immunity genes encoding for AMPs is highly dependent on several signaling cascade pathways, such as the Toll pathway. In the African malaria mosquito,

Indexed as

AnophelesMalariaAnimalsAnti-Bacterial AgentsFemaleHemolymphMyeloid Differentiation Factor 88Anti-Bacterial AgentsMyeloid Differentiation Factor 88antimicrobial peptide (AMP)defensin 1innate immunitymosquitotoll pathwayZOI (zone of inhibition)

Identifiers

PMID36779191
PMCPMC9908765
OpenAlexW4318046808

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.