Evidence map›Paper›PMID 36779079›Full record

ArticleJournal of cardiology cases2023

Fulminant myocarditis with complete atrioventricular block after mRNA COVID-19 vaccination: A case report.

Naoaki Onishi, Yuki Konishi, Toshiyuki Kaneko, Naohiro Maekawa, Akihira Suenaga, Shinnosuke Nomura, Takayasu Kobayashi, Shokan Kyo, Marie Okabayashi, Hirooki Higami and 9 more

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of cardiology cases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 1 institution in 1 country.

Naoaki OnishiDivision of Cardiology, Japanese Red Cross Otsu Hospital, Otsu, Japan.
Yuki KonishiJapanese Red Cross Otsu Hospital, Otsu, Japan.
Toshiyuki KanekoJapanese Red Cross Otsu Hospital, Otsu, Japan.
Naohiro MaekawaJapanese Red Cross Otsu Hospital, Otsu, Japan.
Akihira SuenagaDivision of Cardiology, Japanese Red Cross Otsu Hospital, Otsu, Japan.
Shinnosuke NomuraDivision of Cardiology, Japanese Red Cross Otsu Hospital, Otsu, Japan.
Takayasu KobayashiDivision of Cardiology, Japanese Red Cross Otsu Hospital, Otsu, Japan.
Shokan KyoDivision of Cardiology, Japanese Red Cross Otsu Hospital, Otsu, Japan.
Marie OkabayashiDivision of Cardiology, Japanese Red Cross Otsu Hospital, Otsu, Japan.
Hirooki HigamiDivision of Cardiology, Japanese Red Cross Otsu Hospital, Otsu, Japan.
Maki OiDivision of Cardiology, Japanese Red Cross Otsu Hospital, Otsu, Japan.
Nobuya HigashitaniDivision of Cardiology, Japanese Red Cross Otsu Hospital, Otsu, Japan.
Sayaka SaijoDivision of Cardiology, Japanese Red Cross Otsu Hospital, Otsu, Japan.
Fumiko NakazekiDivision of Cardiology, Japanese Red Cross Otsu Hospital, Otsu, Japan.
Naofumi OyamadaDivision of Cardiology, Japanese Red Cross Otsu Hospital, Otsu, Japan.
Toshikazu JinnaiDivision of Cardiology, Japanese Red Cross Otsu Hospital, Otsu, Japan.
Tomoko OkunoDivision of Pathology, Japanese Red Cross Otsu Hospital, Otsu, Japan.
Tomoyuki ShiraseDivision of Pathology, Japanese Red Cross Otsu Hospital, Otsu, Japan.
Kazuaki KaitaniDivision of Cardiology, Japanese Red Cross Otsu Hospital, Otsu, Japan.
Otsu Red Cross Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 71-year-old man was transferred urgently to our hospital after collapsing near his home post the first shot of the BNT162b2 coronavirus disease 2019 vaccine (Pfizer-BioNTech, Comirnaty®). Immediately after arrival at our hospital, cardiac arrest due to complete atrioventricular block with no ventricular escaped beats was observed on electrocardiogram. Echocardiography showed preserved left ventricular ejection fraction, however, diffuse severe hypokinesia was revealed after 3 weeks, and he died 3 months after admission because of worsening heart failure. An autopsy examination revealed eosinophilic myocarditis or hypersensitivity myocarditis with extensive fibrosis and widespread myocardial dropout throughout the heart. Learning objective: 1. Severe myocarditis occurs extremely rarely after mRNA coronavirus disease 2019 (COVID-19) vaccination. 2. Myocarditis after mRNA COVID-19 vaccination might cause complete atrioventricular block, followed by a course of decreased left ventricular ejection fraction. 3. Histologically, severe myocarditis after mRNA COVID-19 vaccination seems to present as fulminant necrotizing eosinophilic myocarditis or hypersensitivity myocarditis.

Indexed as

BNT162b2Complete atrioventricular blockCoronavirus disease 2019Eosinophilic myocarditisHypersensitivity myocarditismRNA

Identifiers

PMID36779079
PMCPMC9906563
OpenAlexW4318203672

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.