Evidence map›Paper›PMID 36779071›Full record

ArticleFrontiers in neurology2023

Rapid-onset dystonia-parkinsonism is associated with reduced cerebral blood flow without gray matter changes.

Christopher T Whitlow, Kyle M Atcheson, Beverly M Snively, Jared F Cook, Jeongchul Kim, Ihtsham U Haq, Kathleen J Sweadner, Laurie J Ozelius, Allison Brashear

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Structural Alterations in the Gray Matter Volume in Rapid-Onset Dystonia-Parkinsonism.Movement disorders : official journal of the Movement Disorder Society · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Christopher T WhitlowSection of Neuroradiology, Department of Radiology, Wake Forest University School of Medicine, Winston-Salem, NC, United States.
Kyle M AtchesonSection of Neuroradiology, Department of Radiology, Wake Forest University School of Medicine, Winston-Salem, NC, United States.
Beverly M SnivelyClinical and Translational Science Institute, Wake Forest University School of Medicine, Winston-Salem, NC, United States.
Jared F CookDepartment of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, United States.
Jeongchul KimSection of Neuroradiology, Department of Radiology, Wake Forest University School of Medicine, Winston-Salem, NC, United States.
Ihtsham U HaqDepartment of Neurology, University of Miami, Miami, FL, United States.
Kathleen J SweadnerDepartment of Neurosurgery, Massachusetts General Hospital, Boston, MA, United States.
Laurie J OzeliusDepartment of Neurology, Massachusetts General Hospital, Boston, MA, United States.
Allison BrashearDepartment of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, United States.
Wake Forest University · USMassachusetts General Hospital · USUniversity at Buffalo, State University of New York · USUniversity of Miami · US

Funding

Supplement to Clinical, Genetic, and Cellular Consequences of Mutations in Na,K-ATPase ATP1A3R01NS058949 · NINDS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BRASHEAR, ALLISON · 2008 to 2025
$8.9M
NINDS NIH HHS R01 NS058949
6 · The paper itself

Abstract

Purpose: Previous research showed discrete neuropathological changes associated with rapid-onset dystonia-parkinsonism (RDP) in brains from patients with an Methods: Magnetic resonance imaging voxel-based morphometry and arterial spin labeling were used to measure gray matter volume and cerebral blood flow, respectively, in cortical motor areas, basal ganglia, thalamus, and cerebellum, in RDP patients with Results: We report age and sex-adjusted between group differences, with decreased cerebral blood flow among patients with Conclusions: There is reduced cerebral blood flow within brain regions in patients with

Indexed as

arterial spin labelingATP1A3cerebral blood flow (CBF)rapid-onset dystonia-parkinsonism (RDP)voxel-based morphometry

Identifiers

PMID36779071
PMCPMC9909223
OpenAlexW4318054879

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.