Evidence map›Paper›PMID 36779043›Full record

ArticleInfection and drug resistance2023

Pathogen Burden Among ICU Patients in a Tertiary Care Hospital in Hail Saudi Arabia with Particular Reference to β-Lactamases Profile.

Mohd Saleem, Azharuddin Sajid Syed Khaja, Ashfaque Hossain, Fahaad Alenazi, Kamaleldin B Said, Soha Abdallah Moursi, Homoud Abdulmohsin Almalaq, Hamza Mohamed, Ehab Rakha, Mohammed Salem Alharbi and 2 more

Abstract read
In one paragraph

Article in Infection and drug resistance, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Pooled it
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Observational
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mohd SaleemDepartment of Pathology, College of Medicine, University of Hail, Hail, Kingdom of Saudi Arabia.ORCID 0000-0003-2813-6279
Azharuddin Sajid Syed KhajaDepartment of Pathology, College of Medicine, University of Hail, Hail, Kingdom of Saudi Arabia.ORCID 0000-0003-1594-1826
Ashfaque HossainDepartment of Medical Microbiology and Immunology, RAK Medical and Health Sciences University, Ras Al Khaimah, United Arab Emirates.
Fahaad AlenaziDepartment of Pharmacology, College of Medicine, University of Hail, Hail, Kingdom of Saudi Arabia.
Kamaleldin B SaidDepartment of Pathology, College of Medicine, University of Hail, Hail, Kingdom of Saudi Arabia.ORCID 0000-0002-3749-6754
Soha Abdallah MoursiDepartment of Pathology, College of Medicine, University of Hail, Hail, Kingdom of Saudi Arabia.ORCID 0000-0002-3922-2247
Homoud Abdulmohsin AlmalaqHail Health Cluster, King Khalid Hospital, College of Pharmacy, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Hamza MohamedAnatomy Department, Faculty of Medicine, Northern Border University, Arar, Kingdom of Saudi Arabia.ORCID 0000-0002-5666-3140
Ehab RakhaLaboratory Department, King Khalid Hospital, Hail, Kingdom of Saudi Arabia.
Mohammed Salem AlharbiDepartment of Internal Medicine, College of Medicine, University of Hail, Hail, Kingdom of Saudi Arabia.
Salma Ahmed Ali BabikerDepartment of Family Medicine, Hail University Medical Clinics, University of Hail, Hail, Kingdom of Saudi Arabia.
Kauser UsmanDepartment of Internal Medicine, King George's Medical University, Lucknow, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Ventilator-associated pneumonia (VAP) is associated with a higher mortality risk for critical patients in the intensive care unit (ICU). Several strategies, including using β-lactam antibiotics, have been employed to prevent VAP in the ICU. However, the lack of a gold-standard method for VAP diagnosis and a rise in antibiotic-resistant microorganisms have posed challenges in managing VAP. The present study is designed to identify, characterize, and perform antimicrobial susceptibility of the microorganisms from different clinical types of infections in ICU patients with emphasis on VAP patients to understand the frequency of the latter, among others. Patients and Methods: A 1-year prospective study was carried out on patients in the ICU unit at a tertiary care hospital, Hail, Saudi Arabia. Results: A total of 591 clinically suspected hospital-acquired infections (HAI) were investigated, and a total of 163 bacterial isolates were obtained from different clinical specimens with a high proportion of bacteria found associated with VAP (70, 43%), followed by CAUTI (39, 24%), CLABSI (25, 15%), and SSI (14, 8.6%). Conclusion: Proper use of antibiotics, continuous monitoring of drug sensitivity patterns, and taking all precautionary measures to prevent beta-lactamase-producing organisms in clinical settings are crucial and significant factors in fending off life-threatening infections for a better outcome.

Indexed as

Acinetobacter baumanniiESBLICUKlebsiella pneumoniaeVAP

Identifiers

PMID36779043
PMCPMC9911906

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.