ArticleRoyal Society open science2023
The impact of age-related increase in passive muscle stiffness on simulated upper limb reaching.
Article in Royal Society open science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 9 citations in OpenAlex.
- How muscle ageing affects rapid goal-directed movement: mechanistic insights from a simple model.PLoS computational biology · 2026Article
- The effect of age-related sensorimotor changes on step-down strategy: a predictive simulation study.Scientific reports · 2025Article
- Matching dynamically varying forces with multi-motor-unit muscle models: a simulation study.Royal Society open science · 2025Article
- The impact of age-related increase in passive muscle stiffness on simulated upper limb reaching.Royal Society open science · 2023Article
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Authors and funding
2 authors at 1 institution in 1 country.
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Abstract
Ageing changes the musculoskeletal and neural systems, potentially affecting a person's ability to perform daily living activities. One of these changes is increased passive stiffness of muscles, but its contribution to performance is difficult to separate experimentally from other ageing effects such as loss of muscle strength or cognitive function. A computational upper limb model was used to study the effects of increasing passive muscle stiffness on reaching performance across the model's workspace (all points reachable with a given model geometry). The simulations indicated that increased muscle stiffness alone caused deterioration of reaching accuracy, starting from the edges of the workspace. Re-tuning the model's control parameters to match the ageing muscle properties does not fully reverse ageing effects but can improve accuracy in selected regions of the workspace. The results suggest that age-related muscle stiffening, isolated from other ageing effects, impairs reaching performance. The model also exhibited oscillatory instability in a few simulations when the controller was tuned to the presence of passive muscle stiffness. This instability is not observed in humans, implying the presence of natural stabilizing strategies, thus pointing to the adaptive capacity of neural control systems as a potential area of future investigation in age-related muscle stiffening.
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Registered trials
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