Evidence map›Paper›PMID 36778890›Full record

ArticleFrontiers in microbiology2023

Effect of β - hydroxy - γ -aminophosphonate (β - HPC) on the hydrolytic activity of

Sandra Martínez-Robles, Erik González-Ballesteros, Jorge Reyes-Esparza, Isaí Trejo-Teniente, Blanca Estela Jaramillo-Loranca, Alejandro Téllez-Jurado, Víctor H Vázquez-Valadez, Enrique Angeles, Genaro Vargas Hernández

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sandra Martínez-RoblesDepartamento de Ciencias Biológicas, Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de México, Cuautitlán Izcalli, Mexico.
Erik González-BallesterosDepartamento de Ciencias Biológicas, Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de México, Cuautitlán Izcalli, Mexico.
Jorge Reyes-EsparzaFacultad de Farmacia, Universidad Autónoma del Estado de Morelos, Cuernavaca, Mexico.
Isaí Trejo-TenientePrograma Educativo del Posgrado en Biotecnología, Universidad Politécnica de Pachuca, Zempoala, Mexico.
Blanca Estela Jaramillo-LorancaPrograma Educativo del Posgrado en Biotecnología, Universidad Politécnica de Pachuca, Zempoala, Mexico.
Alejandro Téllez-JuradoPrograma Educativo del Posgrado en Biotecnología, Universidad Politécnica de Pachuca, Zempoala, Mexico.
Víctor H Vázquez-ValadezDepartamento de Ciencias Biológicas, Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de México, Cuautitlán Izcalli, Mexico.
Enrique AngelesDepartamento de Ciencias Biológicas, Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de México, Cuautitlán Izcalli, Mexico.
Genaro Vargas HernándezPrograma Educativo del Posgrado en Biotecnología, Universidad Politécnica de Pachuca, Zempoala, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of immunomodulatory and metabolic modulating drugs has been considered a better strategy to improve the efficacy of conventional treatments against pathogens and metabolic diseases. L-carnitine is relevant in fatty acid metabolism and energy production by β-oxidation, but it also has a beneficial therapeutic immunomodulatory effect. The β-hydroxy-γ-aminophosphonate (β-HPC) was developed, synthesized and studied in different pathologies as a more soluble and stable analog than L-carnitine, which has been studied in bacterial physiology and metabolism; therefore, we set out to investigate the direct effect of β-HPC on the metabolism of

Indexed as

caseinegg yolkFT-IRhydrolysisL-carnitine analogL-tyrosineNocardia brasiliensis spectrumTween 80

Identifiers

PMID36778890
PMCPMC9909415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.