Evidence map›Paper›PMID 36778828›Full record

ArticleJournal of anaesthesiology, clinical pharmacology

Effectiveness of ultrasonography-guided cardiac sympathetic denervation in acute control of electrical storm: A retrospective case series.

Suheil Dhanse, Mugula Sudhakar Rao, Padmakumar Ramachandran, Tom Devasia, A J Ashwal, Ganesh Paramasivam, Manjunath Prabhu

Abstract read
In one paragraph

Article in Journal of anaesthesiology, clinical pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Suheil DhanseDepartment of Cardiology, Mahatna Gandhi Missions Medical College and Hospital, Kamothe, Navi Mumbai, Maharashtra, India.
Mugula Sudhakar RaoDepartment of Cardiology, Kasturba Medical College Manipal, Manipal Academy of Higher Education (MAHE), Karnataka, India.
Padmakumar RamachandranDepartment of Cardiology, Kasturba Medical College Manipal, Manipal Academy of Higher Education (MAHE), Karnataka, India.
Tom DevasiaDepartment of Cardiology, Kasturba Medical College Manipal, Manipal Academy of Higher Education (MAHE), Karnataka, India.
A J AshwalDepartment of Cardiology, Kasturba Medical College Manipal, Manipal Academy of Higher Education (MAHE), Karnataka, India.
Ganesh ParamasivamDepartment of Cardiology, Kasturba Medical College Manipal, Manipal Academy of Higher Education (MAHE), Karnataka, India.
Manjunath PrabhuDepartment of Anesthesia, Kasturba Medical College Manipal, Manipal Academy of Higher Education (MAHE), Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Ultrasonography-guided left cardiac sympathetic denervation (LCSD) or bilateral cardiac sympathetic denervation (BCSD) may be a useful intervention in the electrical storm (ES) that persists despite pharmacological therapy. The aim of our study was to evaluate the effectiveness of ultrasonography-guided LCSD or BCSD in the acute control of ES. We conducted a retrospective case series of patients who underwent ultrasonography-guided CSD for control of ES at a tertiary care hospital. Material and Methods: Data of all patients who underwent unilateral or bilateral CSD were collected from January 2017 to December 2019. Eleven patients with ES refractory to standard antiarrhythmic therapy underwent ultrasonography-guided pharmacological CSD (eight underwent LCSD and three underwent BCSD). Quantitative data was expressed as mean and median with interquartile range (IQR). Non-quantitative data was expressed in proportions. Results: Eleven patients underwent ultrasonography-guided pharmacological CSD (eight underwent LCSD and three underwent BCSD). Six of the eleven patients were female (54.5%). Ischemia was the underlying substrate in nine patients (81.8%). Five patients (46%) had complete resolution of ventricular tachycardia (VT) after CSD and one had 90% reduction in episodes of VT. The median follow-up duration was 8 months inter-quartile range IQR (7-18). One patient succumbed to heart failure and one patient was lost to follow up. The other patients had no further events and were well at last follow up. Conclusion: Ultrasonography-guided pharmacological CSD is effective in the acute control of ES. It is easily performed with equipment that is readily available and relatively safe in terms of immediate complications and is an ideal second-line intervention when ES persists despite drug therapy.

Indexed as

Cardiac sympathetic denervationelectrical stormneuraxial modulation

Identifiers

PMID36778828
PMCPMC9912903

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.