Evidence map›Paper›PMID 36778784›Full record

ArticleJournal of molecular and cellular cardiology plus2023

Knockout of ACE-N facilitates improved cardiac function after myocardial infarction.

Hamid Suhail, Hongmei Peng, Jiang Xu, Hani N Sabbah, Khalid Matrougui, Tang-Dong Liao, Pablo A Ortiz, Kenneth E Bernstein, Nour-Eddine Rhaleb

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of molecular and cellular cardiology plus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Hamid SuhailDepartment of Internal Medicine, Hypertension and Vascular Research Division, Henry Ford Hospital, Detroit, MI 48202, USA.
Hongmei PengDepartment of Internal Medicine, Hypertension and Vascular Research Division, Henry Ford Hospital, Detroit, MI 48202, USA.
Jiang XuDepartment of Internal Medicine, Hypertension and Vascular Research Division, Henry Ford Hospital, Detroit, MI 48202, USA.
Hani N SabbahDivision of Cardiovascular Medicine, Department of Internal Medicine, Henry Ford Health, Detroit, MI 48202, USA.
Khalid MatrouguiDepartment of Physiology Sciences, Eastern Virginia Medical School, Norfolk, VA 23501, USA.
Tang-Dong LiaoDepartment of Internal Medicine, Hypertension and Vascular Research Division, Henry Ford Hospital, Detroit, MI 48202, USA.
Pablo A OrtizDepartment of Internal Medicine, Hypertension and Vascular Research Division, Henry Ford Hospital, Detroit, MI 48202, USA.
Kenneth E BernsteinDepartment of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Nour-Eddine RhalebDepartment of Internal Medicine, Hypertension and Vascular Research Division, Henry Ford Hospital, Detroit, MI 48202, USA.
Henry Ford Hospital · USHenry Ford Health System · USCedars-Sinai Medical Center · USEastern Virginia Medical School · US

Funding

Fructose induced salt-sensitive hypertension: Role of thick ascending limb transportR01DK107263 · NIDDK · HENRY FORD HEALTH SYSTEM · PI ORTIZ, PABLO A. · 2016 to 2020
$2.1M
Ac-SDKP in the Treatment of Cardiac Dysfunction in Hypertension or Ischemic HeartR01HL136456 · NHLBI · WAYNE STATE UNIVERSITY · PI RHALEB, NOUR-EDDINE · 2018 to 2021
$1.9M
Interleukin 12 disruption provides beta cell and microvessel protection in type 2diabetesR01HL150014 · NHLBI · OLD DOMINION UNIVERSITY · PI MATROUGUI, KHALID · 2020 to 2023
$1.8M
Stromal interaction molecule 1, immune cells, and vascular pathology in established hypertensionR01HL151616 · NHLBI · OLD DOMINION UNIVERSITY · PI MATROUGUI, KHALID · 2020 to 2023
$1.5M
NHLBI NIH HHS R01 HL136456NHLBI NIH HHS R01 HL150014NHLBI NIH HHS R01 HL151616NIDDK NIH HHS R01 DK107263
6 · The paper itself

Abstract

Angiotensin-converting enzyme (ACE) hydrolyzes

Indexed as

ACE-NAc-SDKPCardiac functionFibrosisMyocardial infarctionSERCA2

Identifiers

PMID36778784
PMCPMC9910327
OpenAlexW4310137277

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.