Evidence map›Paper›PMID 36778748›Full record

ArticleFunction (Oxford, England)2023

Adrenal-Specific KO of the Circadian Clock Protein BMAL1 Alters Blood Pressure Rhythm and Timing of Eating Behavior.

Hannah M Costello, G Ryan Crislip, Kit-Yan Cheng, I Jeanette Lynch, Alexandria Juffre, Phillip Bratanatawira, Annalisse Mckee, Ryanne S Thelwell, Victor M Mendez, Charles S Wingo and 2 more

Open access · goldAbstract read
In one paragraph

Article in Function (Oxford, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Circadian IOP Rhythm in Rats Is Driven by Neural Signals From the Brain.Investigative ophthalmology & visual science · 2026
    Article
  8. Article
  9. Does Anybody Really Know What Time It Is?Function (Oxford, England) · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Current perspective on circadian function of the kidney.American journal of physiology. Renal physiology · 2024
    Review
  15. Review
  16. Determination of the Relationship Between DNA Methylation Status ofBalkan journal of medical genetics : BJMG · 2023
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Hannah M CostelloDepartment of Physiology and Aging, University of Florida, Gainesville, FL 32610, USA.
G Ryan CrislipDepartment of Physiology and Aging, University of Florida, Gainesville, FL 32610, USA.
Kit-Yan ChengDepartment of Physiology and Aging, University of Florida, Gainesville, FL 32610, USA.
I Jeanette LynchDepartment of Medicine, Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, Gainesville, FL 32610, USA.
Alexandria JuffreDepartment of Physiology and Aging, University of Florida, Gainesville, FL 32610, USA.
Phillip BratanatawiraDepartment of Medicine, Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, Gainesville, FL 32610, USA.
Annalisse MckeeDepartment of Physiology and Aging, University of Florida, Gainesville, FL 32610, USA.
Ryanne S ThelwellDepartment of Physiology and Aging, University of Florida, Gainesville, FL 32610, USA.
Victor M MendezDepartment of Physiology and Aging, University of Florida, Gainesville, FL 32610, USA.
Charles S WingoDepartment of Medicine, Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, Gainesville, FL 32610, USA.
Lauren G DoumaDepartment of Physiology and Aging, University of Florida, Gainesville, FL 32610, USA.
Michelle L GumzDepartment of Physiology and Aging, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0002-1342-0878
University of Florida · US

Funding

Per1 and the kidney clock in hypertensionR01DK109570 · NIDDK · UNIVERSITY OF FLORIDA · PI GUMZ, MICHELLE L · 2017 to 2021
$1.5M
The Role of Sex Hormones in Distal Nephron-Specific BMAL1 Blood Pressure Regulation in Male and Female MiceF32DK121424 · NIDDK · UNIVERSITY OF FLORIDA · PI CRISLIP, GENE RYAN · 2019 to 2021
$130k
NIDDK NIH HHS F32 DK121424NIDDK NIH HHS R01 DK109570
6 · The paper itself

Abstract

Brain and muscle ARNT-like 1 (BMAL1) is a core circadian clock protein and transcription factor that regulates many physiological functions, including blood pressure (BP). Male global

Indexed as

ARNTL Transcription FactorsBlood PressureCircadian ClocksFeeding BehaviorAnimalsBrainCorticosteroneMaleMiceMice, KnockoutARNTL Transcription FactorsBmal1 protein, mouseCorticosteroneadrenal glandBlood pressurebrain and muscle ARNT-like 1circadian rhythmscorticosteronefeeding

Identifiers

PMID36778748
PMCPMC9909366
OpenAlexW4313856467

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.