Evidence map›Paper›PMID 36778637›Full record

ArticleFrontiers in psychiatry2023

A multimodal machine learning system in early screening for toddlers with autism spectrum disorders based on the response to name.

Feng-Lei Zhu, Shi-Huan Wang, Wen-Bo Liu, Hui-Lin Zhu, Ming Li, Xiao-Bing Zou

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Data-Driven Approaches for Autism Detection: A Comprehensive Review of Machine Learning Algorithms and Datasets.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Feng-Lei ZhuChild Developmental and Behavioral Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Shi-Huan WangChild Developmental and Behavioral Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Wen-Bo LiuSchool of Electronics and Information Technology, Guangzhou Higher Education Mega Center, Sun Yat-sen University, Guangzhou, China.
Hui-Lin ZhuChild Developmental and Behavioral Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Ming LiData Science Research Center, Duke Kunshan University, Kunshan, China.
Xiao-Bing ZouChild Developmental and Behavioral Center, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Reduced or absence of the response to name (RTN) has been widely reported as an early specific indicator for autism spectrum disorder (ASD), while few studies have quantified the RTN of toddlers with ASD in an automatic way. The present study aims to apply a multimodal machine learning system (MMLS) in early screening for toddlers with ASD based on the RTN. Methods: A total of 125 toddlers were recruited, including ASD ( Results: Total accuracy of RTN scores rated by computers was 0.92. In both evaluator and caregiver procedures, toddlers with ASD had significant differences in response score, response time, and response duration time, compared to toddlers with DD and TD (all Conclusion: The multimodal machine learning system can accurately quantify behaviors in RTN procedures and may effectively distinguish toddlers with ASD from the non-ASD group. This novel system may provide a low-cost approach to early screening and identifying toddlers with ASD. However, machine learning is not as accurate as a human observer, and the detection of a single symptom like RTN is not sufficient enough to detect ASD.

Indexed as

autism spectrum disorder (ASD)early screeningidentificationmachine learningmultimodalresponse to name (RTN)

Identifiers

PMID36778637
PMCPMC9909188

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.