Evidence map›Paper›PMID 36778585›Full record

ArticleCell genomics2021

CanDIG: Federated network across Canada for multi-omic and health data discovery and analysis.

L Jonathan Dursi, Zoltan Bozoky, Richard de Borja, Haoyuan Li, David Bujold, Adam Lipski, Shaikh Farhan Rashid, Amanjeev Sethi, Neelam Memon, Dashaylan Naidoo and 21 more

Abstract readNews
In one paragraph

Article in Cell genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Towards cross-application model-agnostic federated cohort discovery.Journal of the American Medical Informatics Association : JAMIA · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

L Jonathan DursiDATA Team, University Health Network, Toronto, ON, M5G 2C4, Canada.
Zoltan BozokyProvidence Health Care, Vancouver, BC, V6Z 1Y6, Canada.
Richard de BorjaOntario Institute of Cancer Research, Toronto, ON, M5G 0A3, Canada.
Haoyuan LiCanada's Michael Smith Genome Sciences Centre, BC Cancer Research Institute, Provincial Health Services Authority, Vancouver, BC, V5Z 4S6, Canada.
David BujoldCanadian Centre for Computational Genomics, Montréal, QC, H3A 0G1, Canada.
Adam LipskiCanada's Michael Smith Genome Sciences Centre, BC Cancer Research Institute, Provincial Health Services Authority, Vancouver, BC, V5Z 4S6, Canada.
Shaikh Farhan RashidDATA Team, University Health Network, Toronto, ON, M5G 2C4, Canada.
Amanjeev SethiDATA Team, University Health Network, Toronto, ON, M5G 2C4, Canada.
Neelam MemonCanada's Michael Smith Genome Sciences Centre, BC Cancer Research Institute, Provincial Health Services Authority, Vancouver, BC, V5Z 4S6, Canada.
Dashaylan NaidooCanada's Michael Smith Genome Sciences Centre, BC Cancer Research Institute, Provincial Health Services Authority, Vancouver, BC, V5Z 4S6, Canada.
Felipe Coral-SassoCanada's Michael Smith Genome Sciences Centre, BC Cancer Research Institute, Provincial Health Services Authority, Vancouver, BC, V5Z 4S6, Canada.
Matthew WongUniversity of Waterloo, Waterloo, ON, N2L 3G1, Canada.
P-O QuirionCanadian Centre for Computational Genomics, Montréal, QC, H3A 0G1, Canada.
Zhibin LuUniversity Health Network, Toronto, ON, M5G 2C4, Canada.
Samarth AgarwalUniversity of Toronto, Toronto, ON, M5T 3A1, Canada.
Yuriy PavlovDATA Team, University Health Network, Toronto, ON, M5G 2C4, Canada.
Andrew PonomarevCanada's Michael Smith Genome Sciences Centre, BC Cancer Research Institute, Provincial Health Services Authority, Vancouver, BC, V5Z 4S6, Canada.
Mia HusicCentre for Computational Medicine, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada.
Krista PaceDATA Team, University Health Network, Toronto, ON, M5G 2C4, Canada.
Samantha PalmerDATA Team, University Health Network, Toronto, ON, M5G 2C4, Canada.
Stephanie A GroverGenetics and Genome Biology Program, The Hospital for Sick Children, University of Toronto, Toronto, ON, M5G 1X8, Canada.
Sevan HakgorPrincess Margaret Cancer Centre, University Health Network, Toronto, ON, M5G 2C1, Canada.
Lillian L SiuPrincess Margaret Cancer Centre, University Health Network, Toronto, ON, M5G 2C1, Canada.
David MalkinDivision of Haematology/Oncology, The Hospital for Sick Children, Department of Pediatrics, University of Toronto, Toronto, ON, M5G 1X8, Canada.
Carl VirtanenUniversity Health Network, Toronto, ON, M5G 2C4, Canada.
Trevor J PughOntario Institute of Cancer Research, Toronto, ON, M5G 0A3, Canada.
Pierre-Étienne JacquesDépartement de biologie, Université de Sherbrooke, Sherbrooke, QC, J1K 2R1, Canada.
Yann JolyCentre of Genomics and Policy, Department of Human Genetics, McGill University, Montreal, QC, H3A 0C7, Canada.
Steven J M JonesCanada's Michael Smith Genome Sciences Centre, BC Cancer Research Institute, Provincial Health Services Authority, Vancouver, BC, V5Z 4S6, Canada.
Guillaume BourqueDepartment of Human Genetics, McGill University, Montreal, QC, H3A 0C7, Canada.
Michael BrudnoDATA Team, University Health Network, Toronto, ON, M5G 2C4, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the Canadian Distributed Infrastructure for Genomics (CanDIG) platform, which enables federated querying and analysis of human genomics and linked biomedical data. CanDIG leverages the standards and frameworks of the Global Alliance for Genomics and Health (GA4GH) and currently hosts data for five pan-Canadian projects. We describe CanDIG's key design decisions and features as a guide for other federated data systems.

Identifiers

PMID36778585
PMCPMC9903648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.