Evidence map›Paper›PMID 36778533›Full record

ArticleNeuropsychiatric disease and treatment2023

A Novel Metabolic Score for Insulin Resistance and Symptomatic Intracranial Hemorrhage in Ischemic Stroke Patients After Endovascular Thrombectomy.

Shuaiyu Chen, Yan E, Xiaohao Zhang, Bin Wei, Siyu Wang, Zhaohan Xu, Pengyu Gong, Yi Xie, Chunhua Qin, Yingdong Zhang

Abstract read
In one paragraph

Article in Neuropsychiatric disease and treatment, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shuaiyu Chen *Department of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, People's Republic of China.
Yan E *Department of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, People's Republic of China.
Xiaohao Zhang *Department of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, People's Republic of China.ORCID 0000-0002-8916-8592
Bin WeiDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, People's Republic of China.
Siyu WangDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, People's Republic of China.ORCID 0000-0003-2126-0306
Zhaohan XuDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, People's Republic of China.ORCID 0000-0002-0087-7297
Pengyu GongDepartment of Neurology, Affiliated Hospital of Nantong University, Nantong, People's Republic of China.
Yi XieDepartment of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing, People's Republic of China.ORCID 0000-0001-8095-4856
Chunhua QinDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, People's Republic of China.
Yingdong ZhangDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Purpose: Insulin resistance plays a pivotal role in the pathophysiology of ischemic stroke. This study aimed to determine the relationship between the novel metabolic score for insulin resistance (METS-IR) and symptomatic intracranial hemorrhage (sICH) after endovascular thrombectomy (EVT) in stroke patients. Methods: We retrospectively included patients with large artery occlusion in the anterior circulation and treated by EVT from 2 stroke centers (Nanjing First Hospital from September 2019 to April 2022, and Jinling Hospital from September 2019 to July 2021). The METS-IR was used as an alternative marker of insulin resistance and calculated using laboratory data after admission. sICH was diagnosed according to the Heidelberg Bleeding Classification. Results: Of the 410 enrolled patients (mean age, 69.8 ± 11.7 years; 60.7% men), 50 (12.2%) were diagnosed as sICH. After adjusting for demographic characteristics, poor collateral status, and other potential confounders, higher METS-IR was revealed to be independently associated with sICH (odds ratio, 1.076; 95% confidence interval, 1.034-1.120; Conclusion: This study demonstrated a significant association between METS-IR score and sICH in ischemic stroke patients treated with EVT. It could help monitor and manage sICH in patients after EVT.

Indexed as

endovascular thrombectomyinsulin resistanceischemic strokeMETS-IRsymptomatic intracranial hemorrhage

Identifiers

PMID36778533
PMCPMC9910208

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.