Evidence map›Paper›PMID 36778523›Full record

ArticleACS sustainable chemistry & engineering2023

Bioinspired Processing of Keratin into Upcycled Fibers through pH-Induced Coacervation.

Jianwu Sun, Guillermo Monreal Santiago, Feng Yan, Wen Zhou, Petra Rudolf, Giuseppe Portale, Marleen Kamperman

Abstract read
In one paragraph

Article in ACS sustainable chemistry & engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Coacervates as bio-inspired intermediates for materials processing.Chemical communications (Cambridge, England) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jianwu SunPolymer Science, Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.
Guillermo Monreal SantiagoPolymer Science, Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.ORCID https://orcid.org/0000-0002-3754-9270
Feng YanSurfaces and Thin Films, Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.
Wen ZhouProducts and Processes for Biotechnology, Engineering and Technology Institute Groningen, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.
Petra RudolfSurfaces and Thin Films, Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.ORCID https://orcid.org/0000-0002-4418-1769
Giuseppe PortaleMacromolecular Chemistry and New Polymeric Materials, Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.ORCID https://orcid.org/0000-0002-4903-3159
Marleen KampermanPolymer Science, Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.ORCID https://orcid.org/0000-0002-0520-4534

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Keratin is an important byproduct of the animal industry, but almost all of it ends up in landfills due to a lack of efficient recycling methods. To make better use of keratin-based natural resources, the current extraction and processing strategies need to be improved or replaced by more sustainable and cost-effective processes. Here, we developed a simple and environmentally benign method to process extracted keratin, using HCl to induce the formation of a coacervate, a separate aqueous phase with a very high protein concentration. Remarkably, this pH-induced coacervation did not result in the denaturation of keratin, and we could even observe an increase in the amount of ordered secondary structures. The low-pH coacervates could be extruded and wet-spun into high-performance keratin fibers, without requiring heating or any organic solvents. The secondary structure of keratin was largely conserved in these regenerated fibers, which exhibited excellent mechanical performance. The process developed in this study represents a simple and environmentally friendly strategy to upcycle waste keratin into high-performance materials.

Identifiers

PMID36778523
PMCPMC9906721

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.