Evidence map›Paper›PMID 36778505›Full record

ArticleResearch square2023

Peripheral immune-derived matrix metalloproteinase promotes stress susceptibility.

Flurin Cathomas, Hsiao-Yun Lin, Kenny L Chan, Long Li, Romain Durand-de Cuttoli, Lyonna F Parise, Antonio V Aubry, Samer Muhareb, Fiona Desland, Yusuke Shimo and 16 more

Open access · greenAbstract readPreprint
In one paragraph

Article in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

26 authors at 4 institutions in 1 country.

Flurin CathomasNash Family Department of Neuroscience, Brain & Body Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Hsiao-Yun LinNash Family Department of Neuroscience, Brain & Body Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Kenny L ChanNash Family Department of Neuroscience, Brain & Body Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Long LiNash Family Department of Neuroscience, Brain & Body Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-1354-8468
Romain Durand-de CuttoliNash Family Department of Neuroscience, Brain & Body Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0003-0240-7608
Lyonna F PariseNash Family Department of Neuroscience, Brain & Body Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-7527-8977
Antonio V AubryNash Family Department of Neuroscience, Brain & Body Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Samer MuharebNash Family Department of Neuroscience, Brain & Body Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Fiona DeslandDepartment of Oncological Sciences, Precision Immunology Institute, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, NY, USA.
Yusuke ShimoNash Family Department of Neuroscience, Brain & Body Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Aarthi RamakrishnanNash Family Department of Neuroscience, Brain & Body Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Molly EstillNash Family Department of Neuroscience, Brain & Body Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Carmen Ferrer-PérezNash Family Department of Neuroscience, Brain & Body Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Eric M PariseNash Family Department of Neuroscience, Brain & Body Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Jun WangNash Family Department of Neuroscience, Brain & Body Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Allison SowaMicroscopy CoRE and Advanced Bioimaging Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
William G JanssenFriedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Sara CostiDepression and Anxiety Center for Discovery and Treatment, Department of Psychiatry, Icahn School of Medicine of Mount Sinai, New York, NY, USA.
Adeeb RahmanDepartment of Oncological Sciences, Precision Immunology Institute, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, NY, USA.
Nicolas FernandezDepartment of Oncological Sciences, Precision Immunology Institute, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, NY, USA.
Filip K SwirskiCardiovascular Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-3163-9152
Eric J NestlerNash Family Department of Neuroscience, Brain & Body Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-7905-2000
Li ShenNash Family Department of Neuroscience, Brain & Body Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-5190-2851
Miriam MeradDepartment of Oncological Sciences, Precision Immunology Institute, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, NY, USA.ORCID 0000-0002-4481-7827
James W MurroughNash Family Department of Neuroscience, Brain & Body Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0001-6286-1242
Scott J RussoNash Family Department of Neuroscience, Brain & Body Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-6470-1805
Allen Institute for Brain Science · USIcahn School of Medicine at Mount Sinai · USTisch Hospital · USCenter for Discovery · US

Funding

Translational Research CoreP30DK020541 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI STREAMSON C CHUA · 2015 to 2026
$27.7M
ROLE OF PERIPHERAL IMMUNE-DERIVED MMP8 IN STRESS SUSCEPTIBILITYR01MH104559 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SCOTT JAMES RUSSO · 2014 to 2026
$9.2M
Neural Circuit Mechanisms of Stress-Impaired Social RewardR01MH127820 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI RUSSO, SCOTT JAMES · 2021 to 2025
$3.5M
Role of lateral habenula orexin receptor signaling in aggressive social behaviorR01MH114882 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI RUSSO, SCOTT JAMES · 2017 to 2021
$2.7M
NIDDK NIH HHS P30 DK020541NIMH NIH HHS R01 MH104559NIMH NIH HHS R01 MH114882NIMH NIH HHS R01 MH127820
6 · The paper itself

Abstract

Psychosocial stress has profound effects on the body, including the peripheral immune system and the brain

Identifiers

PMID36778505
PMCPMC9915787
OpenAlexW4318481956

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.