Evidence map›Paper›PMID 36778495›Full record

ArticleResearch square2023

Eiko Hayase, Tomo Hayase, Akash Mukherjee, Stuart C Stinson, Mohamed A Jamal, Miriam R Ortega, Christopher A Sanchez, Saira S Ahmed, Jennifer L Karmouch, Chia-Chi Chang and 30 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

40 authors at 4 institutions in 1 country.

Eiko HayaseDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Tomo HayaseDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Akash MukherjeeDepartment of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
Stuart C StinsonDepartment of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
Mohamed A JamalDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Miriam R OrtegaDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Christopher A SanchezDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Saira S AhmedDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Jennifer L KarmouchDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Chia-Chi ChangDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Ivonne I FloresDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Lauren K McDanielDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Alexandria N BrownDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Rawan K El-HimriDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Valerie A ChapaDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Lin TanMetabolomics Core Facility, Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77230, USA.
Bao Q TranMetabolomics Core Facility, Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77230, USA.
Dung PhamDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Taylor M HalseyDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Yimei JinDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Wen-Bin TsaiDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Rishika PrasadDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Israel K GloverDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Nadim J AjamiDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Jennifer A WargoDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Samuel ShelburneDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Pablo C OkhuysenDepartment of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
Chen LiuDepartment of Pathology, Yale School of Medicine, New Haven, Connecticut 06520, USA.
Stephanie W FowlerDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.
Margaret E ConnerDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.
Christine B PetersonDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
Gabriela RondonDepartment of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
Jeffrey J MolldremDepartment of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
Richard E ChamplinDepartment of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
Elizabeth J ShpallDepartment of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
Philip L LorenziMetabolomics Core Facility, Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77230, USA.
Rohtesh S MehtaDepartment of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
Eric C MartensDepartment of Microbiology & Immunology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.
Amin M AlousiDepartment of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
Robert R JenqDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
The University of Texas MD Anderson Cancer Center · USBaylor College of Medicine · USUniversity of Michigan · USYale University · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Protecting colonic mucus to mitigate acute intestinal graft-versus-host diseaseR01HL124112 · NHLBI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI JENQ, ROBERT · 2015 to 2024
$6.8M
New data science approaches to visualize and understand the impact of the microbiome on risk of graft-versus-host diseaseR01HL158796 · NHLBI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI PETERSON, CHRISTINE B · 2022 to 2025
$1.0M
NCI NIH HHS P30 CA016672NHLBI NIH HHS R01 HL124112NHLBI NIH HHS R01 HL158796
6 · The paper itself

Abstract

Acute gastrointestinal intestinal GVHD (aGI-GVHD) is a serious complication of allogeneic hematopoietic stem cell transplantation, and the intestinal microbiota is known to impact on its severity. However, an association between treatment response of aGI-GVHD and the intestinal microbiota has not been well-studied. In a cohort of patients with aGI-GVHD (n=37), we found that non-response to standard therapy with corticosteroids was associated with prior treatment with carbapenem antibiotics and loss of

Indexed as

allogeneic hematopoietic stem cell transplantationBacteroides ovatusBacteroides thetaiotaomicroncarbapenemgraft-versus-host diseaseintestinal microbiomemucus layerpolysaccharidespolysaccharide utilization locixylose

Identifiers

PMID36778495
PMCPMC9915792
OpenAlexW4318563491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.