Evidence map›Paper›PMID 36778491›Full record

ArticlebioRxiv : the preprint server for biology2023

Homodecameric Rad52 promotes single-position Rad51 nucleation in homologous recombination.

Jaigeeth Deveryshetty, Rahul Chadda, Jenna Mattice, Simrithaa Karunakaran, Michael J Rau, Katherine Basore, Nilisha Pokhrel, Noah Englander, James A J Fitzpatrick, Brian Bothner and 1 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jaigeeth DeveryshettyDepartment of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO.
Rahul ChaddaDepartment of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO.
Jenna MatticeDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT.
Simrithaa KarunakaranDepartment of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO.
Michael J RauCenter for Cellular Imaging, Washington University in St. Louis School of Medicine, St. Louis, MO.
Katherine BasoreCenter for Cellular Imaging, Washington University in St. Louis School of Medicine, St. Louis, MO.
Nilisha PokhrelDepartment of Biological Sciences, Marquette University, Milwaukee, WI (Present address: Aera Therapeutics, Boston, MA, USA).
Noah EnglanderDepartment of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO.
James A J FitzpatrickCenter for Cellular Imaging, Washington University in St. Louis School of Medicine, St. Louis, MO.
Brian BothnerDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT.
Edwin AntonyDepartment of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO.

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI AIMEE S JAMES · 2001 to 2026
$128.0M
Research Core (Developmental Research Project Program)P20GM103474 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI Jeffrey Good · 2012 to 2026
$60.0M
Coordination of DNA Metabolism by Replication Protein AR35GM149320 · NIGMS · SAINT LOUIS UNIVERSITY · PI Edwin Antony · 2023 to 2026
$2.3M
Supplement Request for a FluorometerR01GM133967 · NIGMS · SAINT LOUIS UNIVERSITY · PI ANTONY, EDWIN · 2019 to 2023
$1.5M
Mechanisms of DNA hand-off during lesion repair in BER and NER supplementR01GM130746 · NIGMS · SAINT LOUIS UNIVERSITY · PI ANTONY, EDWIN · 2019 to 2022
$1.4M
Acquisition of an Optima Analytical UltracentrifugeS10OD030343 · OD · SAINT LOUIS UNIVERSITY · PI ANTONY, EDWIN · 2021 to 2021
$515k
NCI NIH HHS P30 CA091842NIGMS NIH HHS P20 GM103474NIGMS NIH HHS R01 GM130746NIGMS NIH HHS R01 GM133967NIGMS NIH HHS R35 GM149320NIH HHS S10 OD030343
6 · The paper itself

Abstract

Homologous recombination (HR) is a pathway for the accurate repair of double-stranded DNA breaks. These breaks are resected to yield single-stranded DNA (ssDNA) that are coated by Replication Protein A (RPA).

Identifiers

PMID36778491
PMCPMC9915710

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.