ArticlebioRxiv : the preprint server for biology2024
A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in
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In one paragraph
Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed, 23 citations in OpenAlex.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
48 authors at 14 institutions in 8 countries.
S P MaherCenter for Tropical & Emerging Global Disease, University of Georgia; Athens, GA, 30602, USA.ORCID 0000-0002-9560-5656
M A BakowskiCalibr, a division of The Scripps Research Institute; La Jolla, CA, 92037, USA.ORCID 0000-0002-3337-6528
A VantauxMalaria Molecular Epidemiology Unit, Institute Pasteur of Cambodia; Phnom Penh, 120 210, Cambodia.ORCID 0000-0002-7945-961X
E L FlanneryNovartis Institute for Tropical Diseases, Novartis Institutes for Biomedical Research; Emeryville, CA, 94608, USA.ORCID 0000-0003-0665-7954
C AndolinaShoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit; Mae Sot, Tak, 63110, Thailand.
M GuptaDepartment of Molecular, Cell, and Systems Biology, University of California; Riverside, CA, 92521, USA.
Y Antonova-KochCalibr, a division of The Scripps Research Institute; La Jolla, CA, 92037, USA.ORCID 0000-0003-2862-0407
M ArgomanizCenter for Vaccines and Immunology, College of Veterinary Medicine, University of Georgia; Athens, GA, 30602, USA.
M Cabrera-MoraInternational Center for Malaria Research, Education and Development, Emory Vaccine Center, Emory National Primate Research Center, Emory University; Atlanta, GA, 30329, USA.
B CampoMedicines for Malaria Venture (MMV); Geneva, 1215, Switzerland.
A T ChaoNovartis Institute for Tropical Diseases, Novartis Institutes for Biomedical Research; Emeryville, CA, 94608, USA.
A K ChatterjeeCalibr, a division of The Scripps Research Institute; La Jolla, CA, 92037, USA.ORCID 0000-0001-5171-7982
W T ChengCenter for Vaccines and Immunology, College of Veterinary Medicine, University of Georgia; Athens, GA, 30602, USA.
E ChuenchobNovartis Institute for Tropical Diseases, Novartis Institutes for Biomedical Research; Emeryville, CA, 94608, USA.
C A CooperCenter for Tropical & Emerging Global Disease, University of Georgia; Athens, GA, 30602, USA.ORCID 0000-0002-9994-0291
K CottierBioIVT Inc.; Westbury, NY, 11590, USA.
M R GalinskiInternational Center for Malaria Research, Education and Development, Emory Vaccine Center, Emory National Primate Research Center, Emory University; Atlanta, GA, 30329, USA.
A Harupa-ChungNovartis Institute for Tropical Diseases, Novartis Institutes for Biomedical Research; Emeryville, CA, 94608, USA.
H JiCenter for Vaccines and Immunology, College of Veterinary Medicine, University of Georgia; Athens, GA, 30602, USA.
S B JosephCalibr, a division of The Scripps Research Institute; La Jolla, CA, 92037, USA.
T LenzDepartment of Molecular, Cell, and Systems Biology, University of California; Riverside, CA, 92521, USA.
S LonardiDepartment of Computer Science and Engineering, University of California; Riverside, CA, 92521, USA.ORCID 0000-0002-2696-7274
J MathesonDepartment of Microbiology and Immunology, University of Otago; Dunedin, 9016, New Zealand.ORCID 0000-0002-0222-4679
S A MikolajczakNovartis Institute for Tropical Diseases, Novartis Institutes for Biomedical Research; Emeryville, CA, 94608, USA.ORCID 0000-0003-1996-9703
T MoellerBioIVT Inc.; Westbury, NY, 11590, USA.
A OrbanMalaria Molecular Epidemiology Unit, Institute Pasteur of Cambodia; Phnom Penh, 120 210, Cambodia.
V Padín-IrizarryCenter for Tropical & Emerging Global Disease, University of Georgia; Athens, GA, 30602, USA.ORCID 0000-0002-2810-4501
K PanCalibr, a division of The Scripps Research Institute; La Jolla, CA, 92037, USA.
J PéneauMalaria Molecular Epidemiology Unit, Institute Pasteur of Cambodia; Phnom Penh, 120 210, Cambodia.ORCID 0000-0003-3387-644X
J PrudhommeDepartment of Molecular, Cell, and Systems Biology, University of California; Riverside, CA, 92521, USA.
C RoeschMalaria Molecular Epidemiology Unit, Institute Pasteur of Cambodia; Phnom Penh, 120 210, Cambodia.ORCID 0000-0002-5119-0655
A A RubertoCenter for Tropical & Emerging Global Disease, University of Georgia; Athens, GA, 30602, USA.
S S SabnisCenter for Vaccines and Immunology, College of Veterinary Medicine, University of Georgia; Athens, GA, 30602, USA.
C L SaneyCenter for Vaccines and Immunology, College of Veterinary Medicine, University of Georgia; Athens, GA, 30602, USA.
J SattabongkotMahidol Vivax Research Unit, Mahidol University; Bangkok, 10400, Thailand.ORCID 0000-0002-3938-4588
S SereshkiDepartment of Computer Science and Engineering, University of California; Riverside, CA, 92521, USA.
S SuriyakanShoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit; Mae Sot, Tak, 63110, Thailand.
R UbaleeDepartment of Entomology, Armed Forces Research Institute of Medical Sciences (AFRIMS); Bangkok, 10400, Thailand.
Y WangDepartment of Chemistry, University of California; Riverside, CA, 92521.
P WasisakunShoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit; Mae Sot, Tak, 63110, Thailand.
J YinEnvironmental Toxicology Graduate Program, University of California; Riverside, CA, 92521, USA.
J PopoviciMalaria Molecular Epidemiology Unit, Institute Pasteur of Cambodia; Phnom Penh, 120 210, Cambodia.
C W McNamaraCalibr, a division of The Scripps Research Institute; La Jolla, CA, 92037, USA.ORCID 0000-0002-5754-3407
C J JoynerCenter for Vaccines and Immunology, College of Veterinary Medicine, University of Georgia; Athens, GA, 30602, USA.ORCID 0000-0003-1367-2829
F NostenShoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit; Mae Sot, Tak, 63110, Thailand.ORCID 0000-0002-7951-0745
B WitkowskiMalaria Molecular Epidemiology Unit, Institute Pasteur of Cambodia; Phnom Penh, 120 210, Cambodia.ORCID 0000-0002-8599-6382
K G Le RochDepartment of Molecular, Cell, and Systems Biology, University of California; Riverside, CA, 92521, USA.ORCID 0000-0002-4862-9292
D E KyleCenter for Tropical & Emerging Global Disease, University of Georgia; Athens, GA, 30602, USA.ORCID 0000-0002-0238-965X
University of Georgia · USUniversity of California, Riverside · USScripps Research Institute · USDocumentation Center of Cambodia · KHEmory University · USNovartis (China) · CNShoklo Malaria Research Unit · THSUNY Old Westbury · USAngkor Hospital for Children · KHArmed Forces Research Institute of Medical Science · THDunedin Public Hospital · NZInstitut Pasteur du Cambodge · KHMahidol University · THMedicines for Malaria Venture · CH
Funding
Chromatin structure and control of gene expression in the human malaria parasiteR01AI136511 · NIAID · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI LE ROCH, KARINE GAELLE · 2018 to 2022
$3.4MIllumina NovaSeq 6000 Sequencing SystemS10OD026929 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JEPSEN, KRISTEN LYNN · 2019 to 2019
$600kEvolution of the 3D chromatin structure in apicomplexan parasitesR21AI142506 · NIAID · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI LE ROCH, KARINE GAELLE · 2019 to 2020
$479kNIAID NIH HHS HHSN272201200031CNIAID NIH HHS R01 AI136511NIAID NIH HHS R21 AI142506NIH HHS S10 OD026929Wellcome Trust
Abstract
Radical cure of
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.