Evidence map›Paper›PMID 36778292›Full record

ArticlebioRxiv : the preprint server for biology2023

Sindbis virus is suppressed in the yellow fever mosquito

Sujit Pujhari, Chan C Heu, Marco Brustolin, Rebecca M Johnson, Donghun Kim, Jason L Rasgon

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 3 countries.

Sujit PujhariDepartment of Entomology, the Center for Infectious Disease Dynamics, and the Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA, United States.
Chan C HeuDepartment of Entomology, the Center for Infectious Disease Dynamics, and the Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA, United States.
Marco BrustolinDepartment of Entomology, the Center for Infectious Disease Dynamics, and the Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA, United States.
Rebecca M JohnsonDepartment of Entomology, the Center for Infectious Disease Dynamics, and the Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA, United States.
Donghun KimDepartment of Entomology, the Center for Infectious Disease Dynamics, and the Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA, United States.
Jason L RasgonDepartment of Entomology, the Center for Infectious Disease Dynamics, and the Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA, United States.
Pennsylvania State University · US

Funding

Somatic and germline gene transduction in mosquitoesR01AI128201 · NIAID · PENNSYLVANIA STATE UNIVERSITY, THE · PI Jason L Rasgon · 2017 to 2026
$2.4M
Identification and validation of Zika virus receptor(s) in the midgut lumen of Aedes aegyptiR21AI151475 · NIAID · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI PUJHARI, SUJIT K · 2021 to 2022
$416k
NIAID NIH HHS R01 AI128201NIAID NIH HHS R21 AI151475
6 · The paper itself

Abstract

Autophagy is a critical modulator of pathogen invasion response in vertebrates and invertebrates. However, how it affects mosquito-borne viral pathogens that significantly burden public health remains underexplored. To address this gap, we use a genetic approach to activate macroautophagy/autophagy in the yellow fever mosquito (

Identifiers

PMID36778292
PMCPMC9915692
OpenAlexW4318938711

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.