Evidence map›Paper›PMID 36778221›Full record

ArticlebioRxiv : the preprint server for biology2023

A modular plasmid toolkit applied in marine Proteobacteria reveals functional insights during bacteria-stimulated metamorphosis.

Amanda T Alker, Alpher E Aspiras, Tiffany L Dunbar, Morgan V Farrell, Andriy Fedoriouk, Jeffrey E Jones, Sama R Mikhail, Gabriella Y Salcedo, Bradley S Moore, Nicholas J Shikuma

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Alpher E Aspiras
Tiffany L Dunbar
Morgan V Farrell
Andriy Fedoriouk
Jeffrey E Jones
Sama R Mikhail
Gabriella Y Salcedo
Nicholas J ShikumaORCID 0000-0001-5518-5020

Funding

Examining a Unique Contractile Injection System Mediating Host-Microbe InteractionsR35GM146722 · NIGMS · SAN DIEGO STATE UNIVERSITY · PI Nicholas J Shikuma · 2022 to 2026
$1.9M
NIGMS NIH HHS R35 GM146722
6 · The paper itself

Abstract

A conspicuous roadblock to studying marine bacteria for fundamental research and biotechnology is a lack of modular synthetic biology tools for their genetic manipulation. Here, we applied, and generated new parts for, a modular plasmid toolkit to study marine bacteria in the context of symbioses and host-microbe interactions. To demonstrate the utility of this plasmid system, we genetically manipulated the marine bacterium

Identifiers

PMID36778221
PMCPMC9915575

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.