Evidence map›Paper›PMID 36778137›Full record

ArticleCell genomics2022

Global priorities for large-scale biomarker-based prospective cohorts.

Rory Collins, Mary K Balaconis, Søren Brunak, Zhengming Chen, Mary De Silva, J Michael Gaziano, Geoffrey S Ginsburg, Prabhat Jha, Pablo Kuri, Andres Metspalu and 2 more

Abstract readNews
In one paragraph

Article in Cell genomics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Prospective study design and data analysis in UK Biobank.Science translational medicine · 2024
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rory CollinsNuffield Department of Population Health, University of Oxford, Oxford, UK.
Mary K BalaconisBroad Institute of MIT and Harvard, Cambridge, MA, USA.
Søren BrunakNovo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Zhengming ChenClinical Trial Service Unit & Epidemiological Studies Unit and Medical Research Council Population Health Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Mary De SilvaHead of Population Health, Wellcome Trust, London, UK.
J Michael GazianoDepartment of Medicine, Division of Aging, Brigham and Women's Hospital and the VA Boston Healthcare System, Harvard Medical School, Boston, MA, USA.
Geoffrey S GinsburgAll of Us Research Program, National Institutes of Health, Bethesda, MD, USA.
Prabhat JhaDalla Lana School of Public Health, Centre for Global Health Research, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Pablo KuriInstituto Tecnológico de Estudios Superiores de Monterrey, Monterrey, Mexico.
Andres MetspaluEstonian Genome Center, Institute of Genomics, Estonian Biobank, University of Tartu, Tartu, Estonia.
Nicola MulderDepartment of Integrative Biomedical Sciences, Computational Biology Division, IDM, CIDRI-Africa WT Centre, University of Cape Town, Cape Town, South Africa.
Neil RischInstitute for Human Genetics, University of California, San Francisco, CA, USA.

Funding

Cancer Research UK 29186Medical Research Council MC_PC_14135Medical Research Council MC_U137686851Medical Research Council MC_UU_00017/1Medical Research Council MC_UU_12026/2Wellcome Trust 212946/Z/18/Z
6 · The paper itself

Abstract

The focus of this paper is on strategic approaches for establishing population-based prospective cohorts that collect and store biological samples from very large numbers of participants to help identify the determinants of common health outcomes. In particular, it aims to address key issues related to investigation of genetic, as well as social, environmental, and ancestral, diversity; generation of detailed genetic and other types of assay data; collection of detailed lifestyle and environmental exposure information; follow-up and characterization of incident health outcomes; and overcoming obstacles to data sharing and access (including capacity building). It concludes that there is a need for strategic planning at an international level (rather than the current

Identifiers

PMID36778137
PMCPMC9903754

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.