Evidence map›Paper›PMID 36778054›Full record

ArticleBioMed research international2023

Association of Serum Albumin, Globulin, and Transferrin Levels in Children of Poorly Managed Celiac Disease.

Komal Siddiqui, Arsalan Ahmed Uqaili, Salma Memon, Tazeen Shah, Saima Naz Shaikh, Ali Raza Memon

Abstract read
In one paragraph

Article in BioMed research international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Komal SiddiquiInstitute of Biotechnology and Genetic Engineering, University of Sindh, Jamshoro, Pakistan.
Arsalan Ahmed UqailiDepartment of Physiology, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.ORCID https://orcid.org/0000-0003-3692-3707
Salma MemonDepartment of Physiology, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.ORCID https://orcid.org/0000-0002-9973-0921
Tazeen ShahDepartment of Physiology, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.
Saima Naz ShaikhDepartment of Physiology, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.ORCID https://orcid.org/0000-0001-8767-6510
Ali Raza MemonDepartment of Biochemistry, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Celiac disease (CD) is an autoimmune genetic disorder in which gluten protein causes inflammation of the intestinal enterocytes. CD diagnosis in most cases is delayed or mistreated due to its varied clinical features. We aimed to evaluate the protein profile imbalance in different CD groups of children, which could help aid in the diagnosis and proper management of the disease. Results: The albumin in serum of celiac groups B and C was 3.0 g/dl and 2.8 g/dl, respectively. While in diabetic patients with CD, it is 2.7 g/dl. The globulin levels were raised among all the celiac groups with typical GIT symptoms. The highest transferrin was observed in group B, celiac patients with severe anemia. Patients were not on GFD, hence had no or less recovery and had chronic symptoms of celiac. Conclusion: The misdiagnosis and poor management of celiac leads to chronic villous atrophy with imbalance in metabolic profile. Serum analysis of albumin, globulins, and transferrin may help in the diagnosis and proper management of the disease to recover the celiac symptoms.

Indexed as

Autoimmune DiseasesCeliac DiseaseDiabetes Mellitus, Type 1AdolescentChildChild, PreschoolCross-Sectional StudiesDiet, Gluten-FreeHumansSerum AlbuminTransferrinSerum AlbuminTransferrin

Identifiers

PMID36778054
PMCPMC9908329

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.