ArticleAmerican journal of translational research2023
Influence of early enteral nutrition plus probiotics on intestinal function of senile patients with sepsis.
Article in American journal of translational research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Protective Effect of Xuebijing Injection on Gastrointestinal Function in Septic Patients of Non-Gastrointestinal Origin.Infection and drug resistance · 2026Article
- Intestinal microbial remodeling and metabolite regulation may be related to the improvement of social avoidance in depressed mice by Modified Xiaoyaosan.Frontiers in microbiology · 2026Article
- Effect of postoperative enteral protein supplementation on nitrogen balance in critically ill children.Clinical and experimental pediatrics · 2025Article
- Probiotics: A Little Help for Enteral Nutritional Therapy in Critically Ill Adults.International journal of molecular sciences · 2025Review
- Effects of probiotic treatment on the prognosis of patients with sepsis: a systematic review.World journal of emergency medicine · 2025Review
- Gut Microbiota Metabolites Targeting the Immune Response in Sepsis: Mechanisms and Therapies.International journal of general medicine · 2025Review
- Enhancing sepsis therapy: the evolving role of enteral nutrition.Frontiers in nutrition · 2024Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis research project aimed to discuss the effect of early enteral nutrition (EEN) plus probiotics on intestinal function of senile patients with sepsis.
methods108 senile sepsis patients admitted to our hospital from January 2019 to January 2022 were selected in this retrospective study. These patients including 50 cases in a control group (CG) and 58 cases in a research group (RG). Both groups received EEN, but the research group was given EEN plus probiotics. The two cohorts of patients were compared with respect to treatment efficacy, intestinal mucosal barrier, nutritional status and 28-day mortality. Cox regression was performed to analyze the prognostic factors of elderly patients with sepsis.
resultsCompared to the CG, the RG had evidently higher overall response rate and post-treatment albumin (Alb) and prealbumin (PA) levels, as well as statistically lower intestinal fatty acid binding protein, diamine oxidase, D-lactate and 28-day mortality. Furthermore, Alb and PA were identified as independent predictors of prognosis in elderly patients with sepsis.
conclusionsEEN supplemented with probiotics is superior to EEN alone in the treatment of senile patients with sepsis. This combined regimen can significantly improve intestinal function, nutritional status and prognosis of patients. Moreover, Alb and PA are independently related to the prognosis of elderly patients with sepsis.
Indexed as
Identifiers
36777858PMC9908447What OpenQuestion holds
Registered trials
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