ArticleAmerican journal of translational research2023
Abnormal expression of galectin-1, -3 leading to unexplained infertility by decreasing endometrial receptivity: a retrospective analysis.
Article in American journal of translational research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Implication of the Vaginal Microbiome in Female Infertility and Assisted Conception Outcomes.Genomics, proteomics & bioinformatics · 2025Article
- Maternal and placental galectins: key players in the feto-maternal symbiotic tango.Seminars in immunopathology · 2025Review
- Galectin-1 Elicits a Tissue-Specific Anti-Inflammatory and Anti-Degradative Effect Upon LPS-Induced Response in an Ex Vivo Model of Human Fetal Membranes Modeling an Intraamniotic Inflammation.American journal of reproductive immunology (New York, N.Y. : 1989) · 2024Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo explore the relationship between galectin-1, -3 and unexplained infertility and the effect on endometrial receptivity.
methodsThe clinical data of 100 female patients at childbearing age coming to Xingtai People's Hospital from February 2019 to February 2021 were collected retrospectively. Based on normal pregnancy or not, 50 infertility patients were placed into an infertility group, and 50 patients with normal pregnancy history were placed into a normal group. The mRNA and protein levels of galectin-1, -3, endometrial wave-like activity, endometrial thickness, uterine artery pulsatility index (PI), resistance index (RI), end diastolic velocity (EDV) and peak systolic velocity (PSV) ratio (S/D = PSV/EDV) were compared between the two groups of patients.
resultsThe mRNA and protein levels of galectin-1, -3 in the infertile group were lower than those in the normal group (P<0.05). In addition, the endometrial wave-like activity in the infertile group was more than that in the normal group (P<0.05). The endometrial thickness was less, while PI, RI and S/D were higher in the infertile group than those in the normal group (P<0.05).
conclusionThe low mRNA and protein expressions of galectin-1, -3 in unexplained infertility can affect endometrial receptivity, which may be closely related to unexplained infertility.
Indexed as
Identifiers
36777856PMC9908466What OpenQuestion holds
Registered trials
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