Evidence map›Paper›PMID 36777523›Full record

ArticleEnvironmental epidemiology (Philadelphia, Pa.)2023

Short-term associations between ambient air pollution and emergency department visits for Alzheimer's disease and related dementias.

Haisu Zhang, Liuhua Shi, Stefanie T Ebelt, Rohan R D'Souza, Joel D Schwartz, Noah Scovronick, Howard H Chang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental epidemiology (Philadelphia, Pa.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. The Epidemiological and Toxicological Intersection of Air Pollution and Dementia.Reviews of environmental contamination and toxicology · 2025
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Haisu ZhangGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Liuhua ShiGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Stefanie T EbeltGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Rohan R D'SouzaDepartment of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Joel D SchwartzDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Noah ScovronickGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Howard H ChangGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia.ORCID https://orcid.org/0000-0002-6316-1640

Funding

Data Integration Methods for Environmental Exposures with Applications to Air Pollution and Asthma MorbidityR01ES027892 · NIEHS · EMORY UNIVERSITY · PI CHANG, HOWARD H · 2017 to 2021
$2.7M
NIEHS NIH HHS R01 ES027892
6 · The paper itself

Abstract

Dementia is a seriously disabling illness with substantial economic and social burdens. Alzheimer's disease and its related dementias (AD/ADRD) constitute about two-thirds of dementias. AD/ADRD patients have a high prevalence of comorbid conditions that are known to be exacerbated by exposure to ambient air pollution. Existing studies mostly focused on the long-term association between air pollution and AD/ADRD morbidity, while very few have investigated short-term associations. This study aims to estimate short-term associations between AD/ADRD emergency department (ED) visits and three common air pollutants: fine particulate matter (PM Methods: For the period 2005 to 2015, we analyzed over 7.5 million AD/ADRD ED visits in five US states (California, Missouri, North Carolina, New Jersey, and New York) using a time-stratified case-crossover design with conditional logistic regression. Daily estimated PM Results: The most consistent positive association was found for NO Conclusions: Our results suggest AD/ADRD patients are vulnerable to short-term health effects of ambient air pollution and strategies to lower exposure may reduce morbidity.

Indexed as

Air pollutionAlzheimer’s diseaseDementiaEmergency department visitsHealth effectHospitalization

Identifiers

PMID36777523
PMCPMC9915954

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.