Evidence map›Paper›PMID 36777511›Full record

ArticleAmerican journal of cancer research2023

In silico development and in vitro validation of a novel five-gene signature for prognostic prediction in colon cancer.

Qiankun Zhu, Benqiang Rao, Yongbing Chen, Pingping Jia, Xin Wang, Bingdong Zhang, Lin Wang, Wanni Zhao, Chunlei Hu, Meng Tang and 8 more

Abstract read
In one paragraph

Article in American journal of cancer research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Qiankun ZhuDepartment of General Surgery, Beijing Shijitan Hospital, Capital Medical University Beijing 100038, The People's Republic of China.
Benqiang RaoDepartment of General Surgery, Beijing Shijitan Hospital, Capital Medical University Beijing 100038, The People's Republic of China.
Yongbing ChenDepartment of General Surgery, Beijing Shijitan Hospital, Capital Medical University Beijing 100038, The People's Republic of China.
Pingping JiaDepartment of General Surgery, Beijing Shijitan Hospital, Capital Medical University Beijing 100038, The People's Republic of China.
Xin WangDepartment of General Surgery, Beijing Shijitan Hospital, Capital Medical University Beijing 100038, The People's Republic of China.
Bingdong ZhangDepartment of General Surgery, Beijing Shijitan Hospital, Capital Medical University Beijing 100038, The People's Republic of China.
Lin WangDepartment of General Surgery, Beijing Shijitan Hospital, Capital Medical University Beijing 100038, The People's Republic of China.
Wanni ZhaoDepartment of General Surgery, Beijing Shijitan Hospital, Capital Medical University Beijing 100038, The People's Republic of China.
Chunlei HuDepartment of General Surgery, Beijing Shijitan Hospital, Capital Medical University Beijing 100038, The People's Republic of China.
Meng TangDepartment of General Surgery, Beijing Shijitan Hospital, Capital Medical University Beijing 100038, The People's Republic of China.
Kaiying YuDepartment of General Surgery, Beijing Shijitan Hospital, Capital Medical University Beijing 100038, The People's Republic of China.
Wei ChenNinth School of Clinical Medicine, Peking University Beijing 100038, The People's Republic of China.
Lei PanNinth School of Clinical Medicine, Peking University Beijing 100038, The People's Republic of China.
Yu XuDepartment of General Surgery, The First Affiliated Hospital of Kunming Medical University Kunming 650032, Yunnan, The People's Republic of China.
Huayou LuoDepartment of General Surgery, The First Affiliated Hospital of Kunming Medical University Kunming 650032, Yunnan, The People's Republic of China.
Kunhua WangYunnan University Kunming 650091, Yunnan, The People's Republic of China.
Bo LiDepartment of General Surgery, The Affiliated Hospital of Yunnan University Kunming 650091, Yunnan, The People's Republic of China.
Hanping ShiDepartment of General Surgery, Beijing Shijitan Hospital, Capital Medical University Beijing 100038, The People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colon cancer is one of the most common cancers in digestive system, and its prognosis remains unsatisfactory. Therefore, this study aimed to identify gene signatures that could effectively predict the prognosis of colon cancer patients by examining the data from the Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) database. LASSO-Cox regression analysis generated a five-gene signature (

Indexed as

Colon cancergene signaturepredictionprognosisrisk model

Identifiers

PMID36777511
PMCPMC9906087

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.