ArticleFrontiers in endocrinology2023
Association between body fat and sarcopenia in older adults with type 2 diabetes mellitus: A cross-sectional study.
Article in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 5 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Prevalence of sarcopenic obesity in adult patients with diabetes and associated factors: a systematic review and meta-analysis.Frontiers in nutrition · 2026Pooled it
- Sex-stratified handgrip strength and adipose-derived inflammatory biomarkers in sarcopenia - a systematic review and meta-analysis.BMC geriatrics · 2025Pooled it
- Sarcopenia in type 2 Diabetes mellitus among Asian populations: prevalence and risk factors based on AWGS- 2019: a systematic review and meta-analysis.BMC endocrine disorders · 2025Pooled it
- Association of interleukin-6 with sarcopenia and its components in older adults: a systematic review and meta-analysis of cross-sectional studies.Annals of medicine · 2024Pooled it
- Association between sarcopenia and hemoglobin level: a systematic review and meta-analysis.Frontiers in medicine · 2024Pooled it
- Myoprotective Fat-Loss Phenotypes in Obesity-Associated Type 2 Diabetes: A 12-Month Real-World Cohort Study of Metformin-Based Treatment Regimens.Clinics and practice · 2026Article
- Cardiometabolic index as a predictor of sarcopenia in U.S. adults aged 20-59: results from a cross-sectional study.Clinics (Sao Paulo, Brazil) · 2026Article
- Article
- Body composition-derived principal components partially explain sex and age effects on bone mineral density in type 2 diabetes mellitus.Frontiers in endocrinology · 2026Article
- Weight of time: exploring the link between obesity and aging.Aging clinical and experimental research · 2025Review
- Abdominal and hip fat percentages are associated with fragility fractures: evidence from a large cross-sectional study.Scientific reports · 2025Article
- Association of a Combined Body Mass Index and Regional Body Fat Percentage Metric With Fragility Fracture Risk: Evidence from a Large Observational Cohort.Journal of cachexia, sarcopenia and muscle · 2025Observational
- Association between metabolic score for visceral fat index and BMI-adjusted skeletal muscle mass index in American adults.Lipids in health and disease · 2025Article
- Association between sarcopenia and weight-adjusted waist index in male patients with type 2 diabetes.BMC endocrine disorders · 2025Article
- Association between neutrophil percentage to albumin ratio and sarcopenia among cancer patients: evidence from both the Chinese and American cohorts.Frontiers in nutrition · 2025Article
- Unravelling the obesity maze in diabetic patients: A comparative analysis of classification methods.Journal of family medicine and primary care · 2024Article
- The association between weight-adjusted-waist index and sarcopenia in adults: a population-based study.Scientific reports · 2024Article
- Relationship between sarcopenia and fatty liver in middle-aged and elderly patients with type 2 diabetes mellitus.Journal of orthopaedic surgery and research · 2024Article
- Diabetes Mellitus Should Be Considered While Analysing Sarcopenia-Related Biomarkers.Journal of clinical medicine · 2024Review
- Sarcopenia and diabetes-induced dementia risk.Brain communications · 2024Article
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Authors and funding
6 authors.
Funding
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Abstract
Objectives: To investigate the association between body fat (BF%) and sarcopenia in older adults with type 2 diabetes mellitus (T2DM) and potential link with increased levels of inflammatory indicators and insulin resistance. Methods: A total of 543 older adults with T2DM were included in this cross-sectional study. Appendicular skeletal muscle (ASM), handgrip strength and gait speed were measured to diagnose sarcopenia according to the updated Asian Working Group for Sarcopenia (AWGS) 2019 criteria. Body composition data were tested using dual-energy X-ray absorptiometry (DEXA). Levels of serum high-sensitive C-reactive protein (hs-CRP), interleukin-6, fasting blood insulin (FINS), hemoglobin A1c (HbA1c), 25-hydroxyvitamin D Results: The prevalence of sarcopenia in all participants was 8.84%, of which 11.90% were male and 5.84% females. The Pearson's correlation analysis revealed that BF% was negatively correlated with gait speed in men and women (R =-0.195, Conclusion: Higher BF% was linked to an increased risk of sarcopenia in older adults with T2DM, suggesting the importance of assessing BF% rather than BMI alone to manage sarcopenia.
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