ArticleJournal of biomedical optics2023
Cable-free brain imaging for multiple free-moving animals with miniature wireless microscopes.
Article in Journal of biomedical optics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Miniscope Zero: a fully wireless, single-cell-resolution miniature microscope for imaging neural dynamics in freely behaving animals.bioRxiv : the preprint server for biology · 2026Article
- Tetherless miniaturized point detector device for monitoring cortical surface hemodynamics in mice.Journal of biomedical optics · 2025Article
- How can ethology inform the neuroscience of fear, aggression and dominance?Nature reviews. Neuroscience · 2024Review
- Neurophotonics beyond the surface: unmasking the brain's complexity exploiting optical scattering.Neurophotonics · 2024Article
- Neurophotonics beyond the Surface: Unmasking the Brain's Complexity Exploiting Optical Scattering.ArXiv · 2024Article
- Imaging the brain in action: a motorized optical rotary joint for wide field fibroscopy in freely moving animals.Neurophotonics · 2023Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Significance: Although several miniature microscope systems have been developed to allow researchers to image brain neuron activities of free moving rodents, they generally require a long cable connecting to the miniature microscope. It not only limits the behavior of the animal, but also makes it challenging to study multiple animals simultaneously. Aim: The aim of this work is to develop a fully wireless miniature microscope that would break constraints from the connecting cables so that the animals could move completely freely, allowing neuroscience researchers to study more of animals' behaviors simultaneously, such as social behavior. Approach: We present a wireless mini-microscope (wScope) that enables simultaneously real-time brain imaging preview from multiple free-moving animals. The wScope has a mass of 2.7 g and a maximum frame rate of 25 Hz at Results: The performance of the wScope is validated via real-time imaging of the cerebral blood flow and the activity of neurons in the primary visual cortex (V1) of different mice. Conclusions: The wScope provides a powerful tool for brain imaging of multiple free moving animals in their much larger spaces and more naturalistic environments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.