Evidence map›Paper›PMID 36777246›Full record

ReviewFrontiers in bioengineering and biotechnology2023

Polymeric microcarriers for minimally-invasive cell delivery.

Chunyan Duan, Mingjia Yu, Changji Hu, Hongying Xia, Ranjith Kumar Kankala

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chunyan DuanSchool of New Energy and Environmental Protection Engineering, Foshan Polytechnic, Foshan, China.
Mingjia YuSchool of New Energy and Environmental Protection Engineering, Foshan Polytechnic, Foshan, China.
Changji HuSchool of New Energy and Environmental Protection Engineering, Foshan Polytechnic, Foshan, China.
Hongying XiaFujian Provincial Key Laboratory of Biochemical Technology, Institute of Biomaterials and Tissue Engineering, College of Chemical Engineering, Huaqiao University, Xiamen, China.
Ranjith Kumar KankalaFujian Provincial Key Laboratory of Biochemical Technology, Institute of Biomaterials and Tissue Engineering, College of Chemical Engineering, Huaqiao University, Xiamen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tissue engineering (TE) aims at restoring tissue defects by applying the three-dimensional (3D) biomimetic pre-formed scaffolds to restore, maintain, and enhance tissue growth. Broadly speaking, this approach has created a potential impact in anticipating organ-building, which could reduce the need for organ replacement therapy. However, the implantation of such cell-laden biomimetic constructs based on substantial open surgeries often results in severe inflammatory reactions at the incision site, leading to the generation of a harsh adverse environment where cell survival is low. To overcome such limitations, micro-sized injectable modularized units based on various biofabrication approaches as ideal delivery vehicles for cells and various growth factors have garnered compelling interest owing to their minimally-invasive nature, ease of packing cells, and improved cell retention efficacy. Several advancements have been made in fabricating various 3D biomimetic microscale carriers for cell delivery applications. In this review, we explicitly discuss the progress of the microscale cell carriers that potentially pushed the borders of TE, highlighting their design, ability to deliver cells and substantial tissue growth

Indexed as

injectable architecturesmicrofluidic technologyminimally-invasivepolymeric carrierstissue engineering

Identifiers

PMID36777246
PMCPMC9908582

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.