ArticleJACC. Basic to translational science2023
Reshaping the Ventricle From Within: MIRTH (Myocardial Intramural Remodeling by Transvenous Tether) Ventriculoplasty in Swine.
Article in JACC. Basic to translational science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Ventricular Intramyocardial Navigation for Tachycardia Ablation Guided by Electrograms (VINTAGE): Initial Human Experience.JACC. Clinical electrophysiology · 2025Article
- Transcatheter Coronary Artery Bypass to Circumvent Iatrogenic Obstruction: The VECTOR (Ventriculo-Coronary Transcatheter Outward Navigation and Re-Entry) Procedure in Swine.Circulation. Cardiovascular interventions · 2025Article
- Ventricular intramyocardial navigation for tachycardia ablation guided by electrograms for left ventricular summit arrythmia in a human.HeartRhythm case reports · 2025Article
- Ventricular Intramyocardial Navigation for Tachycardia Ablation Guided by Electrograms (VINTAGE): Deep Ablation in Inaccessible Targets.JACC. Clinical electrophysiology · 2024Article
- Transcatheter Myotomy to Reduce Left Ventricular Outflow Obstruction.Journal of the American College of Cardiology · 2024Article
- Non-invasive pressure-volume loops using the elastance model and CMR: a porcine validation at transient pre-loads.European heart journal. Imaging methods and practice · 2024Article
- EDEN (Electrocardiographic Radial Depth Navigation): A Novel Approach to Navigate Inside Heart Muscle.JACC. Clinical electrophysiology · 2023Article
- Effect of papillary muscle approximation on acute ovine functional tricuspid regurgitation.Interdisciplinary cardiovascular and thoracic surgery · 2023Article
- Transcatheter Electrosurgery: A Narrative Review.Circulation. Cardiovascular interventions · 2023Review
- Device-Based Ventricular Reverse Remodeling: A Multimechanistic Therapeutic Strategy.JACC. Basic to translational science · 2023Article
- Reverse Left Ventricular Remodeling With Transcatheter Interventions in Chronic Heart Failure Syndromes: An Updated Appraisal of the Device Landscape.Journal of the Society for Cardiovascular Angiography & InterventionsReview
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
MIRTH (Myocardial Intramural Remodeling by Transvenous Tether) is a transcatheter ventricular remodeling procedure. A transvenous tension element is placed within the walls of the beating left ventricle and shortened to narrow chamber dimensions. MIRTH uses 2 new techniques: controlled intramyocardial guidewire navigation and EDEN (Electrocardiographic Radial Depth Navigation). MIRTH caused a sustained reduction in chamber dimensions in healthy swine. Midventricular implants approximated papillary muscles. MIRTH shortening improved myocardial contractility in cardiomyopathy in a dose-dependent manner up to a threshold beyond which additional shortening reduced performance. MIRTH may help treat dilated cardiomyopathy. Clinical investigation is warranted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.