Evidence map›Paper›PMID 36777075›Full record

ArticleJournal of clinical biochemistry and nutrition2023

Protective effects of liposomes encapsulating ferulic acid against CCl

Tabassum Ara, Satoko Ono, Mahadi Hasan, Mizune Ozono, Kentaro Kogure

Abstract read
In one paragraph

Article in Journal of clinical biochemistry and nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tabassum AraGraduate School of Pharmaceutical Sciences, Tokushima University, Shomachi 1, Tokushima 770-8505, Japan.
Satoko OnoGraduate School of Pharmaceutical Sciences, Tokushima University, Shomachi 1, Tokushima 770-8505, Japan.
Mahadi HasanResearch Centre for Experimental Modeling of Human Diseases, Kanazawa University, Takaramachi 13-1, Kanazawa 920-8640, Japan.
Mizune OzonoGraduate School of Biomedical Sciences, Tokushima University, Shomachi 1, Tokushima 770-8505, Japan.
Kentaro KogureGraduate School of Biomedical Sciences, Tokushima University, Shomachi 1, Tokushima 770-8505, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antioxidants are useful for the treatment of oxidative stress mediated liver damage. A naturally occurring antioxidant γ-oryzanol is rapidly hydrolyzed to its active hydrophobic metabolite, ferulic acid, inside the body. Limitations associated with the hydrophobicity of ferulic acid can be overcome by encapsulating in a liposomal formulation. As intravenously administered nanoparticles (including liposomes) can effectively reach the liver, such systems may be suitable drug delivery carriers to treat liver injury. In this study, we prepared a liposomal formulation of ferulic acid (ferulic-lipo) and examined its effects on liver damage induced by CCl

Indexed as

CCl4ferulic acidliposomeliver toxicityoxidative stress

Identifiers

PMID36777075
PMCPMC9899917

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.