Evidence map›Paper›PMID 36777036›Full record

ArticleJournal of cellular signaling2022

Redox Homeostasis in Well-differentiated Primary Human Nasal Epithelial Cells.

Ayaho Yamamoto, Peter D Sly, Anna Henningham, Nelufa Begum, Abrey J Yeo, Emmanuelle Fantino

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cellular signaling, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Investigation of CFTR Function in Human Nasal Epithelial Cells Informs Personalized Medicine.American journal of respiratory cell and molecular biology · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ayaho YamamotoChild Health Research Centre, The University of Queensland, South Brisbane, Queensland 4101, Australia.
Peter D SlyChild Health Research Centre, The University of Queensland, South Brisbane, Queensland 4101, Australia.
Anna HenninghamChild Health Research Centre, The University of Queensland, South Brisbane, Queensland 4101, Australia.
Nelufa BegumChild Health Research Centre, The University of Queensland, South Brisbane, Queensland 4101, Australia.
Abrey J YeoChild Health Research Centre, The University of Queensland, South Brisbane, Queensland 4101, Australia.
Emmanuelle FantinoChild Health Research Centre, The University of Queensland, South Brisbane, Queensland 4101, Australia.

Funding

Role of microbiota in increased influenza severity due to particulate matter exposureP42ES013648 · NIEHS · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI SPRUNGER, PHILLIP · 2009 to 2024
$27.6M
NIEHS NIH HHS P42 ES013648
6 · The paper itself

Abstract

Oxidative stress (OS) in the airway epithelium is associated with inflammation, cell damage, and mitochondrial dysfunction that may initiate or worsen respiratory disease. Redox regulation maintains the equilibrium of pro-oxidant/antioxidant reactions but can be disturbed by environmental exposures. The mechanism(s) underlying the induction and impact of OS on airway epithelium and how these influences on respiratory disease is poorly understood. The aim of this study was to develop a stress response model in primary human nasal epithelial cells (NECs) grown at the air-liquid interface (ALI) into a well-differentiated epithelium and to use this model to investigate the mechanisms underlying OS. Hydrogen peroxide (H

Indexed as

Air-liquid interface cultureAirway epitheliumMitochondriaOxidative stressSignaling pathways

Identifiers

PMID36777036
PMCPMC9912202

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.