Evidence map›Paper›PMID 36777022›Full record

ArticleFrontiers in microbiology2022

Regulation of autophagy and lipid accumulation under phosphate limitation in

Ya-Nan Wang, Fang-Jie Liu, Hong-di Liu, Yue Zhang, Xiang Jiao, Ming-Liang Ye, Zong-Bao Kent Zhao, Su-Fang Zhang

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ya-Nan WangLaboratory of Biotechnology, Dalian Institute of Chemical Physics, CAS, Dalian, China.
Fang-Jie LiuLaboratory of Biotechnology, Dalian Institute of Chemical Physics, CAS, Dalian, China.
Hong-di LiuLaboratory of Biotechnology, Dalian Institute of Chemical Physics, CAS, Dalian, China.
Yue ZhangLaboratory of Biotechnology, Dalian Institute of Chemical Physics, CAS, Dalian, China.
Xiang JiaoLaboratory of Biotechnology, Dalian Institute of Chemical Physics, CAS, Dalian, China.
Ming-Liang YeLaboratory of Biotechnology, Dalian Institute of Chemical Physics, CAS, Dalian, China.
Zong-Bao Kent ZhaoLaboratory of Biotechnology, Dalian Institute of Chemical Physics, CAS, Dalian, China.
Su-Fang ZhangLaboratory of Biotechnology, Dalian Institute of Chemical Physics, CAS, Dalian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: It is known that autophagy is essential for cell survival under stress conditions. Inorganic phosphate (Pi) is an essential nutrient for cell growth and Pi-limitation can trigger autophagy and lipid accumulation in oleaginous yeasts, yet protein (de)-phosphorylation and related signaling events in response to Pi limitation and the molecular basis linking Pi-limitation to autophagy and lipid accumulation remain elusive. Results: Here, we compared the proteome and phosphoproteome of Conclusion: Our results provide new insights into autophagy regulation under Pi-limitation and lipid accumulation in oleaginous yeast, which should be valuable to guide further mechanistic study of oleaginicity and genetic engineering for advanced lipid producing cell factory.

Indexed as

Atg9autophagylipid accumulationphosphate limitationRhodotorula toruloides

Identifiers

PMID36777022
PMCPMC9908577

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.