ReviewFrontiers in physiology2023
Pacing interventions in non-responders to cardiac resynchronization therapy.
Review in Frontiers in physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Efficacy of multipoint versus conventional biventricular pacing in CRT: systematic review and meta-analysis of randomized trials.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026Review
- Rapid prediction of cardiac activation in the left ventricle with geometric deep learning: a step towards cardiac resynchronization therapy planning.NPJ digital medicine · 2026Article
- Predictors of patient-perceived functional improvement after cardiac resynchronization therapy: a real-world multi-dimensional analysis of clinical, imaging, and ECG predictors.Frontiers in cardiovascular medicine · 2026Article
- Early occurrence of heart failure hospitalization or ventricular arrhythmia re-define the long-term prognosis after CRT.ESC heart failure · 2025Article
- Multipoint Left Ventricular Pacing as Alternative Approach in Cases of Biventricular Pacing Failure.Journal of clinical medicine · 2025Review
- CineECG Repolarization Gradients Predict Acute Hemodynamic Response in CRT Patients.Journal of cardiovascular electrophysiology · 2025Article
- Article
- Cardiac Contractility Modulation for Heart Failure: Current and Future Directions.Journal of the Society for Cardiovascular Angiography & InterventionsReview
- Narrowing the QRS, Expanding the Function: Left Bundle Branch Pacing in Dilated Cardiomyopathy.Journal of cardiovascular echographyArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Non-responders to Cardiac Resynchronization Therapy (CRT) represent a high-risk, and difficult to treat population of heart failure patients. Studies have shown that these patients have a lower quality of life and reduced life expectancy compared to those who respond to CRT. Whilst the first-line treatment for dyssynchronous heart failure is "conventional" biventricular epicardial CRT, a range of novel pacing interventions have emerged as potential alternatives. This has raised the question whether these new treatments may be useful as a second-line pacing intervention for treating non-responders, or indeed, whether some patients may benefit from these as a first-line option. In this review, we will examine the current evidence for four pacing interventions in the context of treatment of conventional CRT non-responders: CRT optimization; multisite left ventricular pacing; left ventricular endocardial pacing and conduction system pacing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.