Evidence map›Paper›PMID 36776964›Full record

ArticleFrontiers in physiology2023

Single-cell RNA sequencing identifies

Ayako Hanai, Ayako Kawabata, Kenta Nakajima, Kazuhiro Masuda, Itaru Urakawa, Masahiro Abe, Yuji Yamazaki, Seiji Fukumoto

Abstract read
In one paragraph

Article in Frontiers in physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Transcriptomics in the Study of Bone and Cartilage.Current osteoporosis reports · 2026
    Review
  5. Lysophosphatidic Acid Synergizes With 1,25-Dihydroxyvitamin D to Promote Fibroblast Growth Factor-23 Synthesis via MAPK Signaling and Induction of the IL12A Gene.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  6. TGFβ signaling regulates the response of the skeleton to phosphate.bioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ayako HanaiR&D Division, Kyowa Kirin Co., Ltd., Tokyo, Japan.
Ayako KawabataR&D Division, Kyowa Kirin Co., Ltd., Tokyo, Japan.
Kenta NakajimaR&D Division, Kyowa Kirin Co., Ltd., Tokyo, Japan.
Kazuhiro MasudaR&D Division, Kyowa Kirin Co., Ltd., Tokyo, Japan.
Itaru UrakawaR&D Division, Kyowa Kirin Co., Ltd., Tokyo, Japan.
Masahiro AbeDepartment of Endocrinology, Metabolism and Hematology, Tokushima University Graduate School of Medical Sciences, Tokushima, Japan.
Yuji YamazakiR&D Division, Kyowa Kirin Co., Ltd., Tokyo, Japan.
Seiji FukumotoDepartment of Molecular Endocrinology, Fujii Memorial Institute of Medical Sciences, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibroblast growth factor 23 (FGF23), a hormone, mainly produced by osteocytes, regulates phosphate and vitamin D metabolism. By contrast, 1,25-dihydroxyvitamin D

Indexed as

1,25-dihydroxyvitamin D3 (calcitriol)femurFGF23gene expressionosteocytesingle-cell RNA sequencingtranscriptome

Identifiers

PMID36776964
PMCPMC9911654

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.