Evidence map›Paper›PMID 36776864›Full record

ReviewFrontiers in immunology2023

Regulation of mRNA stability contributes to the function of innate lymphoid cells in various diseases.

Yuanyu Deng, Saiyu Shi, Jie Luo, Yiwei Zhang, Hui Dong, Xian Wang, Jian Zhou, Zhiyuan Wei, Jiahui Li, Chen Xu and 7 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Yuanyu DengInstitute of Immunology, PLA, Third Military Medical University (Army Medical University), Chongqing, China.
Saiyu ShiInstitute of Immunology, PLA, Third Military Medical University (Army Medical University), Chongqing, China.
Jie LuoInstitute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.
Yiwei ZhangInstitute of Immunology, PLA, Third Military Medical University (Army Medical University), Chongqing, China.
Hui DongInstitute of Immunology, PLA, Third Military Medical University (Army Medical University), Chongqing, China.
Xian WangDepartment of Immunology, Medical College of Qingdao University, Qingdao, Shandong, China.
Jian ZhouInstitute of Immunology, PLA, Third Military Medical University (Army Medical University), Chongqing, China.
Zhiyuan WeiThe First Affiliated Hospital of Third Military Medical University (Army Medical University), Chongqing, China.
Jiahui LiInstitute of Immunology, PLA, Third Military Medical University (Army Medical University), Chongqing, China.
Chen XuInstitute of Immunology, PLA, Third Military Medical University (Army Medical University), Chongqing, China.
Shuai XuDepartment of Stomatology, Xinqiao Hospital, Third Military Medical University (Army Medical University), Chongqing, China.
Yi SunThe First Affiliated Hospital of Third Military Medical University (Army Medical University), Chongqing, China.
Bing NiDepartment of Pathophysiology, Third Military Medical University (Army Medical University), Chongqing, China.
Yuzhang WuInstitute of Immunology, PLA, Third Military Medical University (Army Medical University), Chongqing, China.
Di YangInstitute of Immunology, PLA, Third Military Medical University (Army Medical University), Chongqing, China.
Chao HanInstitute of Immunology, PLA, Third Military Medical University (Army Medical University), Chongqing, China.
Yi TianInstitute of Immunology, PLA, Third Military Medical University (Army Medical University), Chongqing, China.
Army Medical University · CNQingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Innate lymphoid cells (ILCs) are important subsets of innate immune cells that regulate mucosal immunity. ILCs include natural killer cells, innate lymphoid cells-1 (ILC1s), ILC2s, and ILC3s, which have extremely important roles in the immune system. In this review, we summarize the regulation of mRNA stability mediated through various factors in ILCs (e.g., cytokines, RNA-binding proteins, non-coding RNAs) and their roles in mediating functions in different ILC subsets. In addition, we discuss potential therapeutic targets for diseases such as chronic obstructive pulmonary disease, cancer, and pulmonary fibrosis by regulation of mRNA stability in ILCs, which may provide novel directions for future clinical research.

Indexed as

CytokinesImmunity, InnateKiller Cells, NaturalRNA StabilityCytokinescytokinesILCsmRNA stabilitynon-coding RNARBPs

Identifiers

PMID36776864
PMCPMC9909350
OpenAlexW4318198025

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.