ReviewFrontiers in pediatrics2022
Lactate dehydrogenase and the severity of adenoviral pneumonia in children: A meta-analysis.
Review in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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Who cites it
18 citing papers in PubMed.
- Post-Infectious Bronchiolitis Obliterans as a Model of Immune-Mediated Airway Fibrosis: A Pediatric Case Report.International journal of molecular sciences · 2026Article
- Prognostic implications of lactate dehydrogenase-to-albumin ratio in pediatric intensive care unit patients: a single-center prospective study.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2026Article
- Machine learning-based identification of inflammatory biomarkers for predicting pulmonary consolidation in children with Chlamydia pneumoniae infection.Frontiers in pediatrics · 2026Article
- Lactate Dehydrogenase to Albumin Ratio as a Predictor of Severe Community-Acquired Pneumonia in Patients Aged 60 years and Above: A Retrospective Cohort Study.Infection and drug resistance · 2026Article
- Analysis of Risk Factors and Development of a Predictive Nomogram for Bronchiolitis Obliterans in Children With Severe Adenovirus Pneumonia: A Retrospective Study.Canadian respiratory journal · 2026Article
- Development and validation of a machine learning model for critical progression risk in pediatric severe community-acquired pneumonia.Scientific reports · 2025Article
- Low-dose heparin sodium as a protective factor against bronchiolitis obliterans formation after adenovirus infection.Annals of medicine · 2025Article
- Therapeutic potential of microbiota modulation in psoriasis: current evidence and future directions.Archives of dermatological research · 2025Review
- Development and validation of a machine learning model for in-hospital mortality prediction in children under 5 years with heart failure.Frontiers in pediatrics · 2025Article
- Development and validation of a nomogram for predicting severe adenovirus pneumonia in children.Frontiers in pediatrics · 2025Article
- Nomogram for prediction of plastic bronchitis in Chinese children with pneumonia.Frontiers in pediatrics · 2025Article
- Development and Validation of a Nomogram for Predicting Bronchiolitis Obliterans in Children with Severe Adenovirus Pneumonia: Identification of Key Risk Factors.Pediatric health, medicine and therapeutics · 2025Article
- Prognostic value of the lactate dehydrogenase-to-albumin ratio for predicting mortality in critically ill pediatric patients: a retrospective cohort study.Frontiers in pediatrics · 2025Article
- Serum Cytokines as Predictive Biomarkers for Disease Severity in Pediatric Adenovirus Pneumonia.Journal of inflammation research · 2025Article
- Risk factors and prediction models for bronchiolitis obliterans after severe adenoviral pneumonia.European journal of pediatrics · 2024Article
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- Risk factors for the development of bronchiolitis obliterans in children after suffering from adenovirus pneumonia.Frontiers in pediatrics · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Children with severe adenoviral pneumonia (ADVP) have poor prognosis and high risk of mortality. We performed a meta-analysis to evaluate the association between pretreatment lactate dehydrogenase (LDH) and severity, postinfectious bronchiolitis obliterans (PIBO), and mortality in children with ADVP. Methods: Relevant observational studies were identified by search of PubMed, Embase, Web of Science, Wanfang, and CNKI databases from inception to August 3, 2022. A random effect model was used to pool the results by incorporating the potential between-study heterogeneity. Results: Overall, 23 studies with 4,481 children with ADVP were included in this meta-analysis. Results of meta-analysis showed that children with severe ADVP had a significantly higher level of pretreatment LDH as compared to those with non-severe ADVP (standard mean difference [SMD]: 0.51, 95% confidence interval [CI]: 0.36 to 0.66, Conclusion: High pretreatment LDH may be associated with disease severity, development of PIBO, and increased risk of mortality in children with ADVP.
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