Evidence map›Paper›PMID 36776550›Full record

ArticleFrontiers in cellular and infection microbiology2022

Immunological aspects of host-pathogen crosstalk in the co-pathogenesis of diabetes and latent tuberculosis.

Arpana Verma, Maninder Kaur, Princy Luthra, Lakshyaveer Singh, Divya Aggarwal, Indu Verma, Bishan D Radotra, Sanjay Kumar Bhadada, Sadhna Sharma

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Arpana VermaDepartment of Biochemistry, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Maninder KaurDepartment of Biochemistry, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Princy LuthraDepartment of Biochemistry, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Lakshyaveer SinghTuberculosis Aerosol Challenge Facility (TACF), International Centre for Genetic Engineering and Biotechnology, New Delhi, India.
Divya AggarwalDepartment of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Indu VermaDepartment of Biochemistry, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Bishan D RadotraDepartment of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Sanjay Kumar BhadadaDepartment of Endocrinology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Sadhna SharmaDepartment of Biochemistry, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Post Graduate Institute of Medical Education and Research · INInternational Centre for Genetic Engineering and Biotechnology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Diabetes is a potent risk factor for the activation of latent tuberculosis and worsens the tuberculosis (TB) treatment outcome. The major reason for mortality and morbidity in diabetic patients is due to their increased susceptibility to TB. Thus, the study was conducted to understand the crosstalk between Methods: An animal model was employed to study the relationship between latent tuberculosis and diabetes. BCG immunization was done in mice before infection with Results: A murine model of latent TB was developed, which was confirmed by CFU counts (<10 Discussion: The decreased levels of MCP-1, decreased expression of

Indexed as

Diabetes MellitusLatent TuberculosisMycobacterium tuberculosisTuberculosisAnimalsGlucoseGranulomaMiceGlucosecytokinesdiabetesLatent tuberculosismatrix metalloproteinasestriglyceride synthase

Identifiers

PMID36776550
PMCPMC9909355
OpenAlexW4318065494

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.