ReviewFrontiers in oncology2022
Dose accumulation for MR-guided adaptive radiotherapy: From practical considerations to state-of-the-art clinical implementation.
Review in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Feasibility of dose accumulation for assessing treatment-related side effects in MR-guided abdominal SABR: A single-institution study.Clinical and translational radiation oncology · 2026Article
- Inverse-consistent deformable image registration to propagate biomechanical constraints for online adaptive radiotherapy.Medical physics · 2026Article
- Evaluation of segmentation accuracy and the improvement of time effectiveness using deep learning-based segmentation inEJNMMI physics · 2026Article
- Estimation of accumulated dose to organs at risk in head and neck cancer patients treated with scheduled replanning and dose painting in the ARTFORCE trial.Physics and imaging in radiation oncology · 2026Article
- Evaluation of hybrid DIR performance using controlling structures and points of interest in MR-guided adaptive radiotherapy for prostate cancer patients.Journal of applied clinical medical physics · 2026Article
- Real-time dose reconstruction and dose coverage forecasting using the magnetic resonance linear accelerator.Physics and imaging in radiation oncology · 2026Article
- Local rigidity constraints for deformable image registration in CBCT-guided radiotherapy.Medical physics · 2025Article
- Advanced HyperSight™ imaging for patients with adaptive SBRT of prostate cancer: a longitudinal analysis of tissue demarcation.Radiation oncology (London, England) · 2025Article
- Article
- A viscous fluid model for large-scale motion estimation in image-guided radiotherapy.Medical physics · 2025Article
- Ultrahypofractionated radiotherapy for localised prostate cancer: The impact of daily MRI-guided adaptive radiotherapy on delivered dose.Clinical and translational radiation oncology · 2025Article
- Improving patient specific quality assurance for image registration: clinical use case of target contouring for PET deformable image registration.Physical and engineering sciences in medicine · 2025Article
- Automated daily dose accumulation workflow for treatment quality assurance during online adaptive radiotherapy with a 0.35T MR-linac.Journal of applied clinical medical physics · 2025Article
- An energy-conserving dose summation method for dose accumulation in radiotherapy.Medical physics · 2025Article
- Added value of non-rigid image registration for intrafraction dose accumulation in magnetic resonance imaging-guided prostate radiotherapy.Physics and imaging in radiation oncology · 2025Article
- Geometric evaluation and quantifying dosimetric impact of diverse deformable image registration algorithms on abdomen images with biomechanically modeled deformations.Journal of applied clinical medical physics · 2024Article
- Adaptive assessment based on fractional CBCT images for cervical cancer.Journal of applied clinical medical physics · 2024Article
- Dose tracking assessment for magnetic resonance guided adaptive radiotherapy of rectal cancers.Radiation oncology (London, England) · 2024Article
- MR signature matching (MRSIGMA) implementation for true real-time free-breathing volumetric imaging with sub-200 ms latency on an MR-Linac.Magnetic resonance in medicine · 2024Article
- Deformable dose accumulation is required for adaptive radiotherapy practice.Journal of applied clinical medical physics · 2024Article
Corrections and comments
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Authors and funding
18 authors.
Funding
Abstract
MRI-linear accelerator (MR-linac) devices have been introduced into clinical practice in recent years and have enabled MR-guided adaptive radiation therapy (MRgART). However, by accounting for anatomical changes throughout radiation therapy (RT) and delivering different treatment plans at each fraction, adaptive radiation therapy (ART) highlights several challenges in terms of calculating the total delivered dose. Dose accumulation strategies-which typically involve deformable image registration between planning images, deformable dose mapping, and voxel-wise dose summation-can be employed for ART to estimate the delivered dose. In MRgART, plan adaptation on MRI instead of CT necessitates additional considerations in the dose accumulation process because MRI pixel values do not contain the quantitative information used for dose calculation. In this review, we discuss considerations for dose accumulation specific to MRgART and in relation to current MR-linac clinical workflows. We present a general dose accumulation framework for MRgART and discuss relevant quality assurance criteria. Finally, we highlight the clinical importance of dose accumulation in the ART era as well as the possible ways in which dose accumulation can transform clinical practice and improve our ability to deliver personalized RT.
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