ArticleFrontiers in oncology2023
Pediatric dermatofibrosarcoma protuberans: A clinicopathologic and genetic analysis of 66 cases in the largest institution in Southwest China.
Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Congenital Atrophic Dermatofibrosarcoma Protuberans: A Case Report and Narrative Review of the Literature.Clinical case reports · 2026Article
- Article
- Novel FGL2::PDGFD and TGFBI::PDGFB Fusions Expand the Molecular Spectrum of Dermatofibrosarcoma Protuberans.Genes, chromosomes & cancer · 2026Article
- Beyond COL1A1::PDGFB: Rare fusions and their clinical implications in dermatofibrosarcoma protuberans.World journal of clinical cases · 2025Article
- Darier-Ferrand dermatofibrosarcoma protuberans of the right supraclavicular region in a child: A case report.Radiology case reports · 2025Article
- Scalp Lipofibromatosis - A case report on comprehensive management in a two-year-old child from Pakistan.Pakistan journal of medical sciences · 2024Article
- Paediatric dermatofibrosarcoma protuberan-a case report in an Afro-Caribbean boy.Journal of surgical case reports · 2024Article
- Surgical Management of Pediatric Dermatofibrosarcoma Protuberans: About Two Challenging Case Reports.Global pediatric health · 2024Article
- Dermatofibrosarcoma Protuberans in Children: Favorable Outcomes Using Wide Local Excision.Pediatric dermatologyArticle
- Adequate Diagnostic and Therapeutic Management Practices in Dermatofibrosarcoma Protuberans.Sage open pediatricsArticle
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6 authors.
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Abstract
Background: Dermatofibrosarcoma protuberans (DFSP) is an uncommon cutaneous tumor in children. Most published articles are sporadic or small series and lack systematically molecular analyses. The aim of our study is to better understand the clinicopathologic and genetic features of these rare lesions. Methods: All patients diagnosed with DFSP aged ≤ 18 years were retrospectively reviewed from January 2006 to May 2022. Results: A total of 66 cases (32 male and 34 female patients) were identified, with ages ranging from 0.3 to 18 years (median, 13 years). Tumor locations predominantly occurred on the trunk (38/66, 57.6%), followed by the extremities (20/66, 30.3%) and head/neck (8/66, 12.1%). Histological findings revealed classic (41/66, 62.1%), myxoid (4/66, 6.1%), pigmented (6/66, 9.1%), plaque-like (3/66, 4.5%), giant cell fibroblastoma (GCF; 6/66, 9.1%), and fibrosarcomatous (6/66, 9.1%) variants of DFSP. Immunochemistry revealed minority tumors (9/66, 13.6%) showing patchy or negative staining for CD34. Fluorescence Conclusions: This study of pediatric DFSP indicates certain discrepancies in clinicopathologic characteristics between children and adults. The majority of pediatric DFSPs contain
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