Evidence map›Paper›PMID 36776304›Full record

ArticleFrontiers in oncology2023

Trends in incidence and survival in patients with gastrointestinal neuroendocrine tumors: A SEER database analysis, 1977-2016.

Miao Liu, Lingge Wei, Wei Liu, Shupeng Chen, Meichao Guan, Yingjie Zhang, Ziyu Guo, Ruiqi Liu, Peng Xie

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  6. PredictingEuropean journal of nuclear medicine and molecular imaging · 2026
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  7. Risk Factors Associated with Gastroenteropancreatic and Lung Neuroendocrine Tumors: A Nested Case-Control Study from the All of Us Research Program.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Miao LiuDepartment of Nuclear Medicine, The Third Hospital, Hebei Medical University, Shijiazhuang, Hebei,  China.
Lingge WeiDepartment of Nuclear Medicine, The Third Hospital, Hebei Medical University, Shijiazhuang, Hebei,  China.
Wei LiuDepartment of Nuclear Medicine, The Third Hospital, Hebei Medical University, Shijiazhuang, Hebei,  China.
Shupeng ChenDepartment of Nuclear Medicine, The Third Hospital, Hebei Medical University, Shijiazhuang, Hebei,  China.
Meichao GuanDepartment of Nuclear Medicine, The Third Hospital, Hebei Medical University, Shijiazhuang, Hebei,  China.
Yingjie ZhangDepartment of Nuclear Medicine, The Third Hospital, Hebei Medical University, Shijiazhuang, Hebei,  China.
Ziyu GuoDepartment of Nuclear Medicine, The Third Hospital, Hebei Medical University, Shijiazhuang, Hebei,  China.
Ruiqi LiuDepartment of Nuclear Medicine, Hebei General Hospital, Shijiazhuang, Hebei,  China.
Peng XieDepartment of Nuclear Medicine, The Third Hospital, Hebei Medical University, Shijiazhuang, Hebei,  China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: We aimed to determine trends in incidence and survival in patients with gastrointestinal neuroendocrine tumors (GI-NETs) from 1977 to 2016, and then analyze the potential risk factors including sex, age, race, grade, Socioeconomic status (SES), site, and stage. Methods: Data were obtained from Surveillance, Epidemiology, and End Results Program (SEER) database. Kaplan-Meier survival analysis, relative survival rates (RSRs), and Cox proportional risk regression model were used to evaluate the relationship between these factors and prognosis. Results: Compared with other sites, the small intestine and rectum have the highest incidence, and the appendix and rectum had the highest survival rate. The incidence was higher in males than in females, and the survival rate in males was close to females. Blacks had a higher incidence rate than whites, but similar survival rates. Incidence and survival rates were lower for G3&4 than for G1 and G2. Age, stage, and grade are risk factors. Conclusions: This study described changes in the incidence and survival rates of GI-NETs from 1977 to 2016 and performed risk factor analyses related to GI-NETs.

Indexed as

gastrointestinal neuroendocrine tumorsincidencerelativerisk factorssurvival

Identifiers

PMID36776304
PMCPMC9909535

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.