ArticlePediatric pulmonology2023
Built environment factors predictive of early rapid lung function decline in cystic fibrosis.
Article in Pediatric pulmonology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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Who cites it
10 citing papers in PubMed, 11 citations in OpenAlex.
- Impact of air pollution on lung function in cystic fibrosis over a decade in London: a UK CF Registry study.Thorax · 2026Article
- Racial and Socioeconomic Fairness of Area-Level Traffic-Related Air Pollution Measure Aggregation.medRxiv : the preprint server for health sciences · 2025Article
- Hypercubes to identify geomarkers of rapid cystic fibrosis lung disease progression.BMC medical informatics and decision making · 2025Article
- A Joint Model for (Un)Bounded Longitudinal Markers, Competing Risks, and Recurrent Events Using Patient Registry Data.Statistics in medicine · 2025Article
- Spike and Slab Regression for Nonstationary Gaussian Linear Mixed Effects Modeling of Rapid Disease Progression.Environmetrics · 2025Article
- Robust identification of environmental exposures and community characteristics predictive of rapid lung disease progression.The Science of the total environment · 2024Article
- A New Frontier in Cystic Fibrosis Pathophysiology: How and When Clock Genes Can Affect the Inflammatory/Immune Response in a Genetic Disease Model.Current issues in molecular biology · 2024Review
- Evaluating precision medicine tools in cystic fibrosis for racial and ethnic fairness.Journal of clinical and translational science · 2024Article
- Social-environmental phenotypes of rapid cystic fibrosis lung disease progression in adolescents and young adults living in the United States.Environmental advances · 2023Article
- Social determinants of health, cystic fibrosis-related diabetes, and mental health in adult patients with cystic fibrosis: a critical synthesis of narrative review.Therapeutic advances in respiratory diseaseReview
Corrections and comments
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Authors and funding
17 authors at 5 institutions in 3 countries.
Funding
Abstract
backgroundThe extent to which environmental exposures and community characteristics of the built environment collectively predict rapid lung function decline, during adolescence and early adulthood in cystic fibrosis (CF), has not been examined.
objectiveTo identify built environment characteristics predictive of rapid CF lung function decline.
methodsWe performed a retrospective, single-center, longitudinal cohort study (n = 173 individuals with CF aged 6-20 years, 2012-2017). We used a stochastic model to predict lung function, measured as forced expiratory volume in 1 s (FEV MEASUREMENTS AND MAIN
resultsThe final model, which included ECAT, material deprivation index, and greenspace, alongside traditional demographic/clinical predictors, significantly improved fit and prediction, compared with only demographic/clinical predictors (Likelihood Ratio Test statistic: 26.78, p < 0.0001; the difference in Akaike Information Criterion: 15). An increase of 0.1 μg/m
conclusionTraffic-related air pollution exposure is an important predictor of rapid pulmonary decline that, coupled with community-level material deprivation and routinely collected demographic/clinical characteristics, enhance CF prognostication and enable personalized environmental health interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.