ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023
Thermoresponsive Hydrogel-Enabled Thermostatic Photothermal Therapy for Enhanced Healing of Bacteria-Infected Wounds.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The trial behind it
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Who cites it
23 citing papers in PubMed, 118 citations in OpenAlex.
- Thermal-feedback modality switchable hydrogel with thermoelectric self-modulation for stage-adaptive repair of infected diabetic wound.Nature communications · 2026Article
- Mechanically Active Contractile Hydrogels for Skin Wound Repair.Gels (Basel, Switzerland) · 2026Review
- Innovative applications of multidimensional engineered hydrogels in wound healing.Journal of advanced research · 2026Review
- Dual-responsive PDA-HP hydrogel enables mitochondria-targeted mild photothermal therapy for spinal cord repair.Materials today. Bio · 2026Article
- Analgesic-loaded NIR-II photothermal hydrogel for efficient anti-infection and precise pain management in wounds.Materials today. Bio · 2026Article
- Visible Light-Activated ZnO@CuO Coaxial Nanofibers Enhance Infected Skin Wound Healing Through Construction of p-n Heterojunctions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- SMart Nanoparticle-Hydrogel Hybrid System for Synergistic Eradication of Infection and Promotion of Wound Healing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Engineering a cell wall-deficient protoplast-incorporated hydrogel for infected wound healing.Regenerative biomaterials · 2026Article
- Stimuli-responsive nanomaterials for wound healing: advances and emerging directions.Theranostics · 2026Review
- Nitric oxide releasing graphene for next-generation therapeutics.Advanced drug delivery reviews · 2025Review
- Spatiotemporally controlled delivery of biological effectors from nanofiber scaffolds accelerates skin wound healing in porcine models.Science advances · 2025Article
- Advanced biomaterials for targeting mature biofilms in periodontitis therapy.Bioactive materials · 2025Review
- NIR-triggered programmable nanomotor with HMaterials today. Bio · 2025Article
- Phase-specific and laser-modulated polydopamine-chlorella-curdlan hydrogels: pioneering a melanoma integrative therapy.Theranostics · 2025Article
- A Comprehensive Review of Stimuli-Responsive Smart Polymer Materials-Recent Advances and Future Perspectives.Materials (Basel, Switzerland) · 2024Review
- Harnessing the potential of hydrogels for advanced therapeutic applications: current achievements and future directions.Signal transduction and targeted therapy · 2024Review
- Recent advances on thermosensitive hydrogels-mediated precision therapy.Asian journal of pharmaceutical sciences · 2024Review
- Injectable hydrogels doped with PDA nanoparticles for photothermal bacterial inhibition and rapid wound healingRSC advances · 2024Article
- Photothermal hydrogels for infection control and tissue regeneration.Frontiers in bioengineering and biotechnology · 2024Review
- Smart Responsive and Controlled-Release Hydrogels for Chronic Wound Treatment.Pharmaceutics · 2023Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Photothermal therapy (PTT) has emerged as an attractive technique for the treatment of bacterial infections. However, the uncontrolled heat generation in conventional PTT inevitably causes thermal damages to healthy tissues and/or organs. It is thus essential to develop a smart and universal strategy to regulate the photothermal equilibrium temperature to a preset safe threshold. Herein, a thermoresponsive hydrogel-enabled thermostatic PTT system for enhanced healing of bacteria-infected wounds is reported. In this system, the near-infrared (NIR)-triggered heat generation by photothermal nanomaterials is spontaneously transferred to a thermoresponsive hydrogel with a lower critical solution temperature (LCST), leading to its rapid phase transition by forming considerable light-scattering centers to block NIR penetration. Such a dynamic and reversible process automatically regulates the photothermal equilibrium temperature to the phase-transition point of the LCST-type hydrogel. In contrast to temperature-uncontrolled conventional PTT with severe thermal damages, the thermoresponsive hydrogel-enabled thermostatic PTT provides effective protection on healthy tissues and/or organs, which remarkably accelerates wound healing by efficient bacterial eradication. This study establishes a smart, simple and universal PTT platform, holding great promise in the safe and efficient treatment of bacterial skin infections.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.