Evidence map›Paper›PMID 36775276›Full record

ArticleJournal of clinical neurology (Seoul, Korea)2023

Comparison Between

Kyoungwon Baik, Seun Jeon, Mincheol Park, Young-Gun Lee, Phil Hyu Lee, Young H Sohn, Byoung Seok Ye

Open access · diamondAbstract read
In one paragraph

Article in Journal of clinical neurology (Seoul, Korea), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Comparative study ofBMC neuroscience · 2025
    Article
  6. Cutoff SUVR of [Nuclear medicine and molecular imaging · 2025
    Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kyoungwon Baik *Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-7215-375X
Seun Jeon *Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-2817-3352
Mincheol ParkDepartment of Neurology, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-2714-7494
Young-Gun LeeDepartment of Neurology, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-0460-455X
Phil Hyu LeeDepartment of Neurology, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-9931-8462
Young H SohnDepartment of Neurology, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-6533-2610
Byoung Seok YeDepartment of Neurology, Yonsei University College of Medicine, Seoul, Korea. romel79@gmail.com.ORCID https://orcid.org/0000-0003-0187-8440
Yonsei University · KR

Funding

Korea Health Industry Development Institute HI14C1324
6 · The paper itself

Abstract

background and purposeTo determine the imaging characteristics and cutoff value of

methodsWe prospectively enrolled 35 patients with cognitive impairment who underwent FBB-PET, FC119S-PET, and brain magnetic resonance imaging. We measured global and vertex-wise standardized uptake value ratios (SUVRs) using a surface-based method with the cerebellar gray matter as reference. Optimal global FC119S SUVR cutoffs were determined using receiver operating characteristic curves for β-amyloid positivity based on the global FBB SUVR of 1.478 and presence of AD, respectively. We evaluated the global and vertex-wise SUVR correlations between the two tracers. In addition, we performed correlation analysis for global or vertex-wise SUVR of each tracer with the vertex-wise cortical thicknesses.

resultsThe optimal global FC119S SUVR cutoff value was 1.385 both for detecting β-amyloid positivity and for detecting AD. Based on the global SUVR cutoff value of each tracer, 32 (91.4%) patients had concordant β-amyloid positivity. The SUVRs of FC119S and FBB had strong global (

conclusionsQuantitative FC119S-PET analysis provided reliable information for detecting β-amyloid deposition and the presence of AD.

Indexed as

amyloid-βpositron emission tomography

Identifiers

PMID36775276
PMCPMC10169926
OpenAlexW4320185370

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.