ArticleGenomics, proteomics & bioinformatics2023
Whole-genome Duplication Reshaped Adaptive Evolution in A Relict Plant Species, Cyclocarya paliurus.
Article in Genomics, proteomics & bioinformatics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 27 citations in OpenAlex.
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- Genome-Wide Identification and Expression Analysis of the GH19 Chitinase Gene Family in Sea Island Cotton.Current issues in molecular biology · 2025Article
- Genomic introgression underlies environmental adaptation in three species of Chinese wingnuts,Plant diversity · 2025Article
- Genome Assembly and Winged Fruit Gene Regulation of Chinese Wingnut: Insights from Genomic and Transcriptomic Analyses.Genomics, proteomics & bioinformatics · 2025Article
- Ploidy levels influence cold tolerance of Cyclocarya paliurus: insight into the roles of WRKY genes.BMC genomics · 2025Article
- Seasonal dynamics and molecular regulation of flavonoid biosynthesis inFrontiers in plant science · 2025Article
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- A reference-grade genome of the xerophyte Ammopiptanthus mongolicus sheds light on its evolution history in legumes and drought-tolerance mechanisms.Plant communications · 2024Article
- ThePhysiology and molecular biology of plants : an international journal of functional plant biology · 2024Article
- Genomic insights into biased allele loss and increased gene numbers after genome duplication in autotetraploid Cyclocarya paliurus.BMC biology · 2023Article
- Genome assembly of two diploid and one auto-tetraploid Cyclocarya paliurus genomes.Scientific data · 2023Article
- Article
- Metabolomics and transcriptomics analyses provide new insights into the nutritional quality during the endosperm development of different ploidy rice.Frontiers in plant science · 2023Article
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Authors and funding
20 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Cyclocarya paliurus is a relict plant species that survived the last glacial period and shows a population expansion recently. Its leaves have been traditionally used to treat obesity and diabetes with the well-known active ingredient cyclocaric acid B. Here, we presented three C. paliurus genomes from two diploids with different flower morphs and one haplotype-resolved tetraploid assembly. Comparative genomic analysis revealed two rounds of recent whole-genome duplication events and identified 691 genes with dosage effects that likely contribute to adaptive evolution through enhanced photosynthesis and increased accumulation of triterpenoids. Resequencing analysis of 45 C. paliurus individuals uncovered two bottlenecks, consistent with the known events of environmental changes, and many selectively swept genes involved in critical biological functions, including plant defense and secondary metabolite biosynthesis. We also proposed the biosynthesis pathway of cyclocaric acid B based on multi-omics data and identified key genes, in particular gibberellin-related genes, associated with the heterodichogamy in C. paliurus species. Our study sheds light on evolutionary history of C. paliurus and provides genomic resources to study the medicinal herbs.
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