Evidence map›Paper›PMID 36774803›Full record

ArticleComprehensive psychiatry2023

Childhood and parental characteristics of adults with DSM-5 intermittent explosive disorder compared with healthy and psychiatric controls.

Saba Shevidi, Matthew A Timmins, Emil F Coccaro

Abstract read
In one paragraph

Article in Comprehensive psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Saba ShevidiDepartment of Psychiatry & Behavioral Health, The Ohio State University Wexner Medical Center, 430 Medical Center Drive, Columbus, OH 43210, United States of America.
Matthew A TimminsDepartment of Psychiatry & Behavioral Health, The Ohio State University Wexner Medical Center, 430 Medical Center Drive, Columbus, OH 43210, United States of America.
Emil F CoccaroDepartment of Psychiatry & Behavioral Health, The Ohio State University Wexner Medical Center, 430 Medical Center Drive, Columbus, OH 43210, United States of America. Electronic address: emil.coccaro@osumc.edu.

Funding

Fluoxetine and Divalproex:Treatment Correlates in Intermittent Explosive DisorderR01MH066984 · NIMH · UNIVERSITY OF CHICAGO · PI COCCARO, EMIL FRANK · 2003 to 2007
$3.3M
Intermittent Explosive Disorder: A Family StudyR01MH060836 · NIMH · UNIVERSITY OF CHICAGO · PI COCCA, EMIL FRANK · 2001 to 2005
$2.8M
Neuroinflammation and AggressionR01MH104673 · NIMH · UNIVERSITY OF CHICAGO · PI COCCARO, EMIL FRANK · 2015 to 2018
$2.5M
NIMH NIH HHS R01 MH060836NIMH NIH HHS R01 MH066984NIMH NIH HHS R01 MH104673
6 · The paper itself

Abstract

backgroundIntermittent Explosive Disorder (IED) is a disorder primarily of aggression, defined by recurrent behavioral outbursts out of proportion to provocations or stressors. IED first appears in childhood and adolescence. This study examines the underlying childhood environment of those with IED, particularly familial and school-related factors.

methodsAdult participants from a larger study completed diagnostic assessments and a battery of self-report measures. Group assignment was based on the assessment: 1) IED diagnosis; 2) non-IED psychiatric diagnosis; and 3) no significant psychiatric history. Groups were compared on factors of parental demographics, intrafamilial aggression, lifetime syndromal and personality diagnoses, neurodevelopmental and learning difficulties, childhood peer relationships, and juvenile legal issues.

resultsSignificant patterns emerged specific to IED for not being raised by both parents, greater physical aggression to participant, and greater degree of fighting with peers by age ten. LIMITATIONS: The retrospective, and cross-sectional, nature of the study, which prevent the making of causal inferences, and the basic nature of the questions asked of participants which limit a more nuanced interpretation of the data. A further limitation is bias associated with self-reported responses.

conclusionsResults suggest the prevalence childhood adversaries may be linked with IED; the childhood environment of those with IED likely is substantially more tumultuous than individuals with or without other psychiatric disorders.

Indexed as

Disruptive, Impulse Control, and Conduct DisordersAdolescentAdultAggressionCross-Sectional StudiesHumansParentsRetrospective StudiesAggressionBehavioral issuesIEDParental characteristics

Identifiers

PMID36774803
PMCPMC10262303

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.