Evidence map›Paper›PMID 36774357›Full record

ArticleNature communications2023

Virtual elastography ultrasound via generative adversarial network for breast cancer diagnosis.

Zhao Yao, Ting Luo, YiJie Dong, XiaoHong Jia, YinHui Deng, GuoQing Wu, Ying Zhu, JingWen Zhang, Juan Liu, LiChun Yang and 34 more

Abstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  7. Mechanomedicine.Nature reviews bioengineering · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

44 authors.

Zhao Yao *School of Information Science and Technology, Fudan University, Shanghai, China.
Ting Luo *Department of Ultrasound, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200025, China.
YiJie Dong *Department of Ultrasound, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200025, China.
XiaoHong Jia *Department of Ultrasound, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200025, China.
YinHui Deng *School of Information Science and Technology, Fudan University, Shanghai, China.ORCID 0000-0001-8287-6134
GuoQing WuSchool of Information Science and Technology, Fudan University, Shanghai, China.
Ying ZhuDepartment of Ultrasound, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200025, China.
JingWen ZhangDepartment of Ultrasound, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200025, China.
Juan LiuDepartment of Ultrasound, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200025, China.
LiChun YangDepartment of Medical Ultrasound, Yunnan Cancer Hospital & The Third Affiliated Hospital of Kunming Medical University, Kunming, 650118, China.
XiaoMao LuoDepartment of Medical Ultrasound, Yunnan Cancer Hospital & The Third Affiliated Hospital of Kunming Medical University, Kunming, 650118, China.
ZhiYao LiDepartment of Medical Ultrasound, Yunnan Cancer Hospital & The Third Affiliated Hospital of Kunming Medical University, Kunming, 650118, China.
YanJun XuDepartment of Ultrasound in Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Institute of Ultrasound in Medicine, Shanghai, 200233, China.
Bin HuDepartment of Ultrasound, Minhang Hospital, Fudan University, Shanghai, 201199, China.
YunXia HuangDepartment of Ultrasonography, Fudan University Shanghai Cancer Center, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Cai ChangDepartment of Ultrasonography, Fudan University Shanghai Cancer Center, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
JinFeng XuDepartment of Ultrasound, Shenzhen People's Hospital, Guangzhou, Guangdong, China.
Hui LuoDepartment of Ultrasound, Shenzhen People's Hospital, Guangzhou, Guangdong, China.
FaJin DongDepartment of Ultrasound, Shenzhen People's Hospital, Guangzhou, Guangdong, China.ORCID 0000-0002-4558-4885
XiaoNa XiaDepartment of Ultrasound Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.
ChengRong WuDepartment of Ultrasound Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.
WenJia HuDepartment of Ultrasound, People's Hospital of Henan Province, Zhengzhou, 450000, China.
Gang WuDepartment of Ultrasound, People's Hospital of Henan Province, Zhengzhou, 450000, China.
QiaoYing LiDepartment of Ultrasound Diseases, Tangdu Hospital, Four Military Medical University, Xi'an, 710038, China.
Qin ChenDepartment of Ultrasound, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 610072, China.
WanYue DengDepartment of Ultrasound, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 610072, China.
QiongChao JiangDepartment of Ultrasound, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.
YongLin MouDepartment of Ultrasound, General Hospital of Northern Theater Command, 110000, Shenyang, China.
HuanNan YanDepartment of Ultrasound, General Hospital of Northern Theater Command, 110000, Shenyang, China.
XiaoJing XuDepartment of Ultrasound, Affiliated Hangzhou First people's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, China.
HongJu YanDepartment of Ultrasound, Affiliated Hangzhou First people's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, China.
Ping ZhouDepartment of Ultrasound, The Third Xiangya Hospital of Central South University, Changsha, 410013, China.
Yang ShaoDepartment of Ultrasound, The Third Xiangya Hospital of Central South University, Changsha, 410013, China.
LiGang CuiDepartment of Ultrasound, Peking University Third Hospital, Beijing, 100191, China.
Ping HeDepartment of Ultrasound, Peking University Third Hospital, Beijing, 100191, China.
LinXue QianDepartment of Ultrasound, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
JinPing LiuDepartment of Ultrasound, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
LiYing ShiDepartment of Ultrasound, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, 550004, China.
YaNan ZhaoDepartment of Ultrasound, Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, 310009, China.
YongYuan XuDepartment of Ultrasound, Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, 310009, China.
WeiWei ZhanDepartment of Ultrasound, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200025, China.
YuanYuan WangSchool of Information Science and Technology, Fudan University, Shanghai, China.ORCID 0000-0003-1984-1136
JinHua YuSchool of Information Science and Technology, Fudan University, Shanghai, China. jhyu@fudan.edu.cn.ORCID 0000-0002-0654-6034
JianQiao ZhouDepartment of Ultrasound, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200025, China. zhousu30@126.com.ORCID 0000-0002-0964-8407

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Elastography ultrasound (EUS) imaging is a vital ultrasound imaging modality. The current use of EUS faces many challenges, such as vulnerability to subjective manipulation, echo signal attenuation, and unknown risks of elastic pressure in certain delicate tissues. The hardware requirement of EUS also hinders the trend of miniaturization of ultrasound equipment. Here we show a cost-efficient solution by designing a deep neural network to synthesize virtual EUS (V-EUS) from conventional B-mode images. A total of 4580 breast tumor cases were collected from 15 medical centers, including a main cohort with 2501 cases for model establishment, an external dataset with 1730 cases and a portable dataset with 349 cases for testing. In the task of differentiating benign and malignant breast tumors, there is no significant difference between V-EUS and real EUS on high-end ultrasound, while the diagnostic performance of pocket-sized ultrasound can be improved by about 5% after V-EUS is equipped.

Indexed as

Breast NeoplasmsElasticity Imaging TechniquesDiagnosis, DifferentialEndosonographyFemaleHumansSensitivity and SpecificityUltrasonography

Identifiers

PMID36774357
PMCPMC9922312

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.