Evidence map›Paper›PMID 36774123›Full record

ArticleThe Journal of nutrition2022

Dietary Exposure to Toxic Elements and the Health of Young Children: Methodological Considerations and Data Needs.

Katarzyna Kordas, Alejandra Cantoral, Gauri Desai, Olivia Halabicky, Antonio J Signes-Pastor, Martha M Tellez-Rojo, Karen E Peterson, Margaret R Karagas

Open access · greenAbstract read
In one paragraph

Article in The Journal of nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 3 countries.

Katarzyna KordasDepartment of Epidemiology and Environmental Health, University at Buffalo, Buffalo NY, USA. Electronic address: kkordas@buffalo.edu.
Alejandra CantoralHealth Department, Universidad Iberoamericana, Mexico City, Mexico.
Gauri DesaiDepartment of Epidemiology and Environmental Health, University at Buffalo, Buffalo NY, USA.
Olivia HalabickyDepartment of Nutritional Sciences, University of Michigan, Ann Arbor, MI, USA.
Antonio J Signes-PastorUnidad de Epidemiología de la Nutrición, Universidad Miguel Hernández, Alicante, Spain; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III (ISCIII), Madrid, Spain; Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL), Alicante, Spain.
Martha M Tellez-RojoCenter for Nutrition and Health Research, Instituto Nacional de Salud Pública, Cuernavaca, Morelos, Mexico.
Karen E PetersonDepartment of Nutritional Sciences, University of Michigan, Ann Arbor, MI, USA; Department of Environmental Health Sciences, University of Michigan, Ann Arbor, MI, USA.
Margaret R KaragasDepartment of Epidemiology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
University of Michigan · USDartmouth College · USIbero American University · MXInstituto Nacional de Salud Pública · MXKaleida Health · USUniversitat de Miguel Hernández d'Elx · ESUniversity at Buffalo, State University of New York · US

Funding

A prospective study of critical environmental exposures in formative early life that impact lifelong health in rural US children: the New Hampshire Birth Cohort StudyUH3OD023275 · OD · DARTMOUTH COLLEGE · PI MARGARET Rita KARAGAS, Juliette Madan · 2018 to 2026
$44.3M
Relation Between In-utero Vitamin D and Immune Function in Early Childhood P20GM104416 · NIGMS · DARTMOUTH COLLEGE · PI SALAS DIAZ, LUCAS A · 2013 to 2022
$23.7M
Strategic Vision & Impact on Environmental HealthP30ES017885 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Dana Dolinoy · 2011 to 2026
$21.3M
ENVIRONMENTAL TOXICOLOGY PRE/POST DOCTORAL RES.TRAININGT32ES007062 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Justin Adam Colacino · 1985 to 2026
$10.5M
E3Gen: Multigenerational Influences of Social Structure on Toxicant Exposures and Life Course Health in the ELEMENT CohortR24ES028502 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Karen Eileen Peterson, Peter Xuekun Song · 2017 to 2026
$2.2M
NIEHS NIH HHS P30 ES017885NIEHS NIH HHS R24 ES028502NIEHS NIH HHS T32 ES007062NIGMS NIH HHS P20 GM104416NIH HHS UH3 OD023275
6 · The paper itself

Abstract

Concerns have been raised regarding toxic-element (arsenic, cadmium, lead, and mercury) contamination of commercially available infant foods around the world. Young children are vulnerable to the effects of toxic elements, based on higher absorption levels and potentially poorer detoxification capacities. Toxic-element exposures in early life exact high societal costs, but it is unclear how much dietary exposure to these elements contributes to adverse health outcomes. Well-designed epidemiological studies conducted in different geographical and socioeconomic contexts need to estimate dietary toxicant exposure in young children and to determine whether causal links exist between toxicants in children's diets and health outcomes. This commentary outlines the methodological considerations and data needs to advance such research.

Indexed as

ArsenicMercuryCadmiumChildChild, PreschoolDietDietary ExposureEnvironmental ExposureHumansInfantArsenicCadmiumMercurychild healthdietfood safetymetalstoxicant exposure

Identifiers

PMID36774123
PMCPMC10157815
OpenAlexW4301394006

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.