ArticleAnnals of epidemiology2023
Application of Life's Essential 8 to assess cardiovascular health during early childhood.
Article in Annals of epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cardiovascular Health, 2010 to 2020: A Systematic Review of a Decade of Research on Life's Simple 7.Journal of the American Heart Association · 2025Pooled it
- Early-Life Sociodemographic Factors and Cardiovascular Health in Preadolescence Among Low-Income and Racially and Ethnically Diverse Children.Journal of the American Heart Association · 2025Trial
- Design of the School-Based SI! Program Reintervention Trial for Child Health Promotion.JACC. Advances · 2026Article
- Decreased ultra-processed food consumption as a mediator for lowering cardiovascular risk after a lifestyle program in pediatric obesity: a randomized clinical trial.Frontiers in nutrition · 2026Article
- Racial and ethnic disparities in childhood cardiovascular health: evidence of the role of social disadvantage from NHANES 2013-2018.BMC medicine · 2025Article
- Trajectory of Cardiovascular Health Across Childhood and Adolescence.JAMA cardiology · 2025Article
- Prenatal and Perinatal Factors of Life's Essential 8 Cardiovascular Health Trajectories.JAMA network open · 2025Article
- 2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association.Circulation · 2025Review
- Associations between gestational exposure to neighbourhood socioeconomic deprivation and early childhood weight status.Pediatric obesity · 2025Article
- Association between Life's Essential 8 and depression: a population-based study.Archives of medical science : AMS · 2025Article
- The predictive utility of the in utero exposome for childhood adiposity in independent and integrated frameworks.Pediatric obesity · 2024Article
- Association of life's essential 8 with prevalence and all-cause mortality of chronic kidney disease among US adults: Results from the National Health and Nutrition Examination Survey (2015-2018).Journal of translational internal medicine · 2024Article
- Associations between AHA's Life's Essential 8 and cognition in midlife and older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Cardiovascular health assessed by the new life's essential 8 and the prevalence of urinary incontinence in adults.BMC public health · 2024Article
- Sociodemographic Correlates of High Cardiovascular Health Across Childhood and Adolescence: A Prospective Study Among 2 Cohorts in the ECHO Consortium.Journal of the American Heart Association · 2024Article
- The Use of Life's Essential 8 as a Prediction Model and Beyond.JACC. Advances · 2024Article
- Food Insecurity and Ideal Cardiovascular Health Risk Factors Among US Adolescents.Journal of the American Heart Association · 2024Article
- 2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association.Circulation · 2024Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
purposeAssess cardiovascular health (CVH) during early childhood using the American Heart Association's recently updated construct, Life's Essential 8 (LE8); examine concordance in CVH status per LE8 versus Life's Simple 7 (LS7); and identify perinatal correlates of high CVH per LE8.
methodsWe applied LE8 and LS7 to data from 305 children aged 4-7 years in Denver, CO; estimated % low, moderate, high, and optimal CVH; assessed concordance in CVH status based on LE8 and LS7 using contingency tables; and used multivariable logistic regression to identify early-life correlates of high CVH per LE8.
resultsAverage age of children was 4.7 ± 0.6 years, 44.6% were female. No participants had low or optimal CVH, 43.9% had high, and 56.1% had moderate CVH per LE8, whereas 33.4% had high and 66.6% had moderate CVH per LS7. Twenty-two percent had high CVH based on both constructs. Correlates of high CVH were maternal prenatal diet quality (odds ratio
conclusionsLE8 yielded higher prevalence of high CVH than LS7 during early childhood, though there is modest concordance between the two constructs. Maternal diet is a potential modifiable target to optimize early-life CVH.
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Registered trials
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