Evidence map›Paper›PMID 36773768›Full record

ArticleGastroenterology2023

Genetically Engineered Mouse Models Shine New Light on Decades-old Story of Trypsin in Pancreatitis.

Bomi Lee, Sohail Z Husain, Ilya Gukovsky

Abstract readEditorialComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Pathologically relevant trypsinogen activation in pancreatitis.American journal of physiology. Gastrointestinal and liver physiology · 2026
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Bomi LeeDivision of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Stanford University, Stanford, California.
Sohail Z HusainDivision of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, Stanford University, Stanford, California. Electronic address: Sohail.husain@stanford.edu.
Ilya GukovskyDepartment of Medicine, University of California at Los Angeles, and VA Greater Los Angeles Healthcare System, Los Angeles, California.

Funding

Calcineurin in pancreatitisR01DK093491 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HUSAIN, SOHAIL Z · 2011 to 2020
$3.7M
Impaired autophagy, mitochondrial dysfunction, and inflammation in pancreatitisR01DK131111 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GUKOVSKY, ILYA, LEE, BOMI · 2022 to 2025
$1.5M
Lysosomal Damage, Impaired Autophagy, and Alcoholic PancreatitisR01AA019730 · NIAAA · BRENTWOOD BIOMEDICAL RESEARCH INSTITUTE · PI GUKOVSKY, ILYA, MARENINOVA, OLGA A · 2011 to 2015
$1.4M
NIAAA NIH HHS R01 AA019730NIDDK NIH HHS R01 DK093491NIDDK NIH HHS R01 DK131111
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

PancreatitisAnimalsMiceTrypsinTrypsin InhibitorsTrypsinogenTrypsinTrypsin InhibitorsTrypsinogen

Identifiers

PMID36773768
PMCPMC10680306

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.